Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography

<b>Introduction:</b> This study aimed to determine the frequency of posterior vitreous detachment (PVD) in dry and wet age-related macular degeneration (AMD) patients compared with healthy eyes via ultrawide field optical coherence tomography (UWF–OCT). Additionally, the retinal thicknes...

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Main Authors: Maciej Gawęcki, Krzysztof Kiciński, Andrzej Grzybowski, Sławomir Teper
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/11/1382
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author Maciej Gawęcki
Krzysztof Kiciński
Andrzej Grzybowski
Sławomir Teper
author_facet Maciej Gawęcki
Krzysztof Kiciński
Andrzej Grzybowski
Sławomir Teper
author_sort Maciej Gawęcki
collection DOAJ
description <b>Introduction:</b> This study aimed to determine the frequency of posterior vitreous detachment (PVD) in dry and wet age-related macular degeneration (AMD) patients compared with healthy eyes via ultrawide field optical coherence tomography (UWF–OCT). Additionally, the retinal thicknesses in the central and peripheral zones of AMD patients and the control group were compared. <b>Methods:</b> We included 123 eyes from 83 participants with dry AMD, 123 from 87 participants with wet AMD, and 85 from 53 healthy controls. All three study groups were compared according to age, sex, best corrected visual acuity (BCVA), PVD stage, axial length, and retinal thickness in the central, perifoveal, and peripheral zones. Additional analyses included correlations between the BCVA and PVD stage and between retinal thickness and the PVD stage. <b>Results:</b> Complete separation of the vitreous from the macula was significantly more common in AMD patients than in the control group, as noted in 47 eyes (55.29%) in the control group, 92 eyes (74.80%) in the wet AMD group, and 93 eyes (75.61%) in the dry AMD group. The PVD stage did not significantly influence retinal thickness. BCVA in AMD patients did not correlate with the PVD stage. <b>Conclusions:</b> Complete PVD is more common in AMD patients than in healthy controls, as evaluated by UWF–OCT. No relationship between the PVD stage and AMD type or BCVA was observed.
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spelling doaj-art-34aafb43bceb46f285e5b1c651f4eac82025-08-20T02:32:55ZengMDPI AGDiagnostics2075-44182025-05-011511138210.3390/diagnostics15111382Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence TomographyMaciej Gawęcki0Krzysztof Kiciński1Andrzej Grzybowski2Sławomir Teper3Department of Ophthalmology of Pomeranian Hospitals, 84-120 Wejherowo, PolandDepartment of Ophthalmology of Pomeranian Hospitals, 84-120 Wejherowo, PolandDepartment of Ophthalmology, University of Warmia and Mazury, Oczapowskiego 2, 10-719 Olsztyn, PolandChair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-752 Katowice, Poland<b>Introduction:</b> This study aimed to determine the frequency of posterior vitreous detachment (PVD) in dry and wet age-related macular degeneration (AMD) patients compared with healthy eyes via ultrawide field optical coherence tomography (UWF–OCT). Additionally, the retinal thicknesses in the central and peripheral zones of AMD patients and the control group were compared. <b>Methods:</b> We included 123 eyes from 83 participants with dry AMD, 123 from 87 participants with wet AMD, and 85 from 53 healthy controls. All three study groups were compared according to age, sex, best corrected visual acuity (BCVA), PVD stage, axial length, and retinal thickness in the central, perifoveal, and peripheral zones. Additional analyses included correlations between the BCVA and PVD stage and between retinal thickness and the PVD stage. <b>Results:</b> Complete separation of the vitreous from the macula was significantly more common in AMD patients than in the control group, as noted in 47 eyes (55.29%) in the control group, 92 eyes (74.80%) in the wet AMD group, and 93 eyes (75.61%) in the dry AMD group. The PVD stage did not significantly influence retinal thickness. BCVA in AMD patients did not correlate with the PVD stage. <b>Conclusions:</b> Complete PVD is more common in AMD patients than in healthy controls, as evaluated by UWF–OCT. No relationship between the PVD stage and AMD type or BCVA was observed.https://www.mdpi.com/2075-4418/15/11/1382posterior vitreous detachmentultrawide field OCTretinal thicknessAMD
spellingShingle Maciej Gawęcki
Krzysztof Kiciński
Andrzej Grzybowski
Sławomir Teper
Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography
Diagnostics
posterior vitreous detachment
ultrawide field OCT
retinal thickness
AMD
title Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography
title_full Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography
title_fullStr Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography
title_full_unstemmed Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography
title_short Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography
title_sort posterior vitreous detachment in healthy versus amd eyes assessed by widefield optical coherence tomography
topic posterior vitreous detachment
ultrawide field OCT
retinal thickness
AMD
url https://www.mdpi.com/2075-4418/15/11/1382
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AT krzysztofkicinski posteriorvitreousdetachmentinhealthyversusamdeyesassessedbywidefieldopticalcoherencetomography
AT andrzejgrzybowski posteriorvitreousdetachmentinhealthyversusamdeyesassessedbywidefieldopticalcoherencetomography
AT sławomirteper posteriorvitreousdetachmentinhealthyversusamdeyesassessedbywidefieldopticalcoherencetomography