Randomized clinical trial of peer integrated collaborative care intervention after physical injury

Objectives The goal of the current study was to assess the effectiveness of a peer integrated collaborative care intervention for postinjury outcomes.Methods Injury survivors ≥18 years of age were screened for post-traumatic stress disorder (PTSD) symptoms and severe postinjury concerns; screen-posi...

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Main Authors: Eileen M Bulger, Peter Thomas, Jin Wang, Lauren K Whiteside, Ronald Maier, Allison Engstrom, Douglas F Zatzick, Joan Russo, Patrick Heagerty, Khadija Abu, Tanya Knutzen, Jake Shoyer, Navneet Birk, Cristina Conde, Paige Ryan, Matt Iles-Shih, Lawrence Palinkas
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:Trauma Surgery & Acute Care Open
Online Access:https://tsaco.bmj.com/content/10/1/e001657.full
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author Eileen M Bulger
Peter Thomas
Jin Wang
Lauren K Whiteside
Ronald Maier
Allison Engstrom
Douglas F Zatzick
Joan Russo
Patrick Heagerty
Khadija Abu
Tanya Knutzen
Jake Shoyer
Navneet Birk
Cristina Conde
Paige Ryan
Matt Iles-Shih
Lawrence Palinkas
author_facet Eileen M Bulger
Peter Thomas
Jin Wang
Lauren K Whiteside
Ronald Maier
Allison Engstrom
Douglas F Zatzick
Joan Russo
Patrick Heagerty
Khadija Abu
Tanya Knutzen
Jake Shoyer
Navneet Birk
Cristina Conde
Paige Ryan
Matt Iles-Shih
Lawrence Palinkas
author_sort Eileen M Bulger
collection DOAJ
description Objectives The goal of the current study was to assess the effectiveness of a peer integrated collaborative care intervention for postinjury outcomes.Methods Injury survivors ≥18 years of age were screened for post-traumatic stress disorder (PTSD) symptoms and severe postinjury concerns; screen-positive patients were randomized to the intervention versus enhanced usual care control conditions. The collaborative care intervention included peer support and care management. The intervention also included evidence-based pharmacotherapy and psychotherapeutic elements targeting PTSD. The COVID-19 pandemic interrupted recruitment between March and June 2020; in response to the COVID-19 pandemic, the peer component of the intervention went from in-person to virtual delivery. The primary outcomes were PTSD symptoms assessed with the Diagnostic and Statistical Manual of Mental Disorders fourth edition PTSD checklist, any severe postinjury concerns, and emergency department/inpatient utilization followed over the 12 months postinjury. Secondary outcomes included patient satisfaction with emotional healthcare.Results A total of 450 patients were randomized to the intervention (n=225) and control (n=225) conditions; 124 patients (28%) were recruited and completed all study assessments prior to the onset of the COVID-19 pandemic, while 326 patients (72%) were recruited after and/or had one or more study follow-ups occur postpandemic onset. Mixed model regression revealed no statistically significant comparisons for any of the primary outcomes. In exploratory models that examined the impact of COVID-19, significantly improved PTSD symptoms were present at 3 months pre-COVID-19 relative to post-COVID-19. Intervention patients consistently demonstrated higher satisfaction with emotional aspects of healthcare (F(5,1652)=2.87, p=0.01).Conclusions The intervention demonstrated no significant improvements in primary outcomes in the intent-to-treat sample. The peer integrated collaborative care intervention contributed to higher patient satisfaction with the emotional aspects of healthcare.Level of evidence Level II, randomized clinical trial.Trial registration number NCT03569878.
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spelling doaj-art-34a2207fc95a4fe69a9fb4d173eee1a32025-08-20T01:50:39ZengBMJ Publishing GroupTrauma Surgery & Acute Care Open2397-57762025-03-0110110.1136/tsaco-2024-001657Randomized clinical trial of peer integrated collaborative care intervention after physical injuryEileen M Bulger0Peter Thomas1Jin Wang2Lauren K Whiteside3Ronald Maier4Allison Engstrom5Douglas F Zatzick6Joan Russo7Patrick Heagerty8Khadija Abu9Tanya Knutzen10Jake Shoyer11Navneet Birk12Cristina Conde13Paige Ryan14Matt Iles-Shih15Lawrence Palinkas162 Department of Surgery, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA3 Department of Pediatrics, University of Washington, Seattle, Washington, USA6 Department of Emergency Medicine, University of Washington School of Medicine, Seattle, Washington, USA2 Department of Surgery, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA5 Department of Biostatistics, University of Washington School of Public Health, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA1 Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA4 Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California, USAObjectives The goal of the current study was to assess the effectiveness of a peer integrated collaborative care intervention for postinjury outcomes.Methods Injury survivors ≥18 years of age were screened for post-traumatic stress disorder (PTSD) symptoms and severe postinjury concerns; screen-positive patients were randomized to the intervention versus enhanced usual care control conditions. The collaborative care intervention included peer support and care management. The intervention also included evidence-based pharmacotherapy and psychotherapeutic elements targeting PTSD. The COVID-19 pandemic interrupted recruitment between March and June 2020; in response to the COVID-19 pandemic, the peer component of the intervention went from in-person to virtual delivery. The primary outcomes were PTSD symptoms assessed with the Diagnostic and Statistical Manual of Mental Disorders fourth edition PTSD checklist, any severe postinjury concerns, and emergency department/inpatient utilization followed over the 12 months postinjury. Secondary outcomes included patient satisfaction with emotional healthcare.Results A total of 450 patients were randomized to the intervention (n=225) and control (n=225) conditions; 124 patients (28%) were recruited and completed all study assessments prior to the onset of the COVID-19 pandemic, while 326 patients (72%) were recruited after and/or had one or more study follow-ups occur postpandemic onset. Mixed model regression revealed no statistically significant comparisons for any of the primary outcomes. In exploratory models that examined the impact of COVID-19, significantly improved PTSD symptoms were present at 3 months pre-COVID-19 relative to post-COVID-19. Intervention patients consistently demonstrated higher satisfaction with emotional aspects of healthcare (F(5,1652)=2.87, p=0.01).Conclusions The intervention demonstrated no significant improvements in primary outcomes in the intent-to-treat sample. The peer integrated collaborative care intervention contributed to higher patient satisfaction with the emotional aspects of healthcare.Level of evidence Level II, randomized clinical trial.Trial registration number NCT03569878.https://tsaco.bmj.com/content/10/1/e001657.full
spellingShingle Eileen M Bulger
Peter Thomas
Jin Wang
Lauren K Whiteside
Ronald Maier
Allison Engstrom
Douglas F Zatzick
Joan Russo
Patrick Heagerty
Khadija Abu
Tanya Knutzen
Jake Shoyer
Navneet Birk
Cristina Conde
Paige Ryan
Matt Iles-Shih
Lawrence Palinkas
Randomized clinical trial of peer integrated collaborative care intervention after physical injury
Trauma Surgery & Acute Care Open
title Randomized clinical trial of peer integrated collaborative care intervention after physical injury
title_full Randomized clinical trial of peer integrated collaborative care intervention after physical injury
title_fullStr Randomized clinical trial of peer integrated collaborative care intervention after physical injury
title_full_unstemmed Randomized clinical trial of peer integrated collaborative care intervention after physical injury
title_short Randomized clinical trial of peer integrated collaborative care intervention after physical injury
title_sort randomized clinical trial of peer integrated collaborative care intervention after physical injury
url https://tsaco.bmj.com/content/10/1/e001657.full
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