High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years
Background Takotsubo cardiomyopathy continues to be a major cause of mortality and morbidity. The goal of this study was to evaluate the outcome data of patients with Takotsubo cardiomyopathy using a large inpatient database. Methods and Results We used the Nationwide Inpatient Sample database for o...
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| Format: | Article |
| Language: | English |
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Wiley
2025-05-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
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| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.037219 |
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| author | Mohammad Reza Movahed Elimira Javanmardi Mehrtash Hashemzadeh |
| author_facet | Mohammad Reza Movahed Elimira Javanmardi Mehrtash Hashemzadeh |
| author_sort | Mohammad Reza Movahed |
| collection | DOAJ |
| description | Background Takotsubo cardiomyopathy continues to be a major cause of mortality and morbidity. The goal of this study was to evaluate the outcome data of patients with Takotsubo cardiomyopathy using a large inpatient database. Methods and Results We used the Nationwide Inpatient Sample database for our study. We evaluated trends, mortality, and complications of patients admitted with Takotsubo cardiomyopathy from available years 2016 to 2020 in adults >18. A total of 199 890 patients with Takotsubo were found in our database with 83% being female and higher prevalence with age, White race, and highest income. Mortality was high at 6.5% with no significant improvement over the years studied. Furthermore, major complications were substantial. Cardiogenic shock occurred in 6.6%, atrial fibrillation in 20.7%, cardiac arrest in 3.4%, congestive heart failure in 35.9%, and stroke in 5.3%. Mortality was more than double in men in comparison to women (11.2% versus 5.5%). Conclusions Takotsubo cardiomyopathy is associated with high mortality and complications with no improvement in outcome over the 5‐year study with higher mortality in men. Further improvement in care is needed to improve outcomes. |
| format | Article |
| id | doaj-art-349d38c4ecfc463cb99c7cc99e0b702e |
| institution | DOAJ |
| issn | 2047-9980 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj-art-349d38c4ecfc463cb99c7cc99e0b702e2025-08-20T03:07:23ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802025-05-01141010.1161/JAHA.124.037219High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the YearsMohammad Reza Movahed0Elimira Javanmardi1Mehrtash Hashemzadeh2University of Arizona Sarver Heart Center Tucson AZ USAUniversity of Arizona Sarver Heart Center Tucson AZ USACollege of Medicine University of Arizona Phoenix AZ USABackground Takotsubo cardiomyopathy continues to be a major cause of mortality and morbidity. The goal of this study was to evaluate the outcome data of patients with Takotsubo cardiomyopathy using a large inpatient database. Methods and Results We used the Nationwide Inpatient Sample database for our study. We evaluated trends, mortality, and complications of patients admitted with Takotsubo cardiomyopathy from available years 2016 to 2020 in adults >18. A total of 199 890 patients with Takotsubo were found in our database with 83% being female and higher prevalence with age, White race, and highest income. Mortality was high at 6.5% with no significant improvement over the years studied. Furthermore, major complications were substantial. Cardiogenic shock occurred in 6.6%, atrial fibrillation in 20.7%, cardiac arrest in 3.4%, congestive heart failure in 35.9%, and stroke in 5.3%. Mortality was more than double in men in comparison to women (11.2% versus 5.5%). Conclusions Takotsubo cardiomyopathy is associated with high mortality and complications with no improvement in outcome over the 5‐year study with higher mortality in men. Further improvement in care is needed to improve outcomes.https://www.ahajournals.org/doi/10.1161/JAHA.124.037219apical ballooning syndromecardiogenic shockcardiomyopathycomplicationsstress induced cardiomyopathy |
| spellingShingle | Mohammad Reza Movahed Elimira Javanmardi Mehrtash Hashemzadeh High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease apical ballooning syndrome cardiogenic shock cardiomyopathy complications stress induced cardiomyopathy |
| title | High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years |
| title_full | High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years |
| title_fullStr | High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years |
| title_full_unstemmed | High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years |
| title_short | High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years |
| title_sort | high mortality and complications in patients admitted with takotsubo cardiomyopathy with more than double mortality in men without improvement in outcome over the years |
| topic | apical ballooning syndrome cardiogenic shock cardiomyopathy complications stress induced cardiomyopathy |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.124.037219 |
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