Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade

Abstract Diatoms, a major group of microalgae, play a critical role in global carbon cycling and primary production. Despite their ecological significance, comprehensive genomic resources for diatoms are limited. To address this, we have annotated previously unannotated genome assemblies of 49 diato...

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Main Authors: Natalia Nenasheva, Clara Pitzschel, Cynthia N. Webster, Alexander J. Hart, Jill L. Wegrzyn, Mia M. Bengtsson, Katharina J. Hoff
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-05306-z
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author Natalia Nenasheva
Clara Pitzschel
Cynthia N. Webster
Alexander J. Hart
Jill L. Wegrzyn
Mia M. Bengtsson
Katharina J. Hoff
author_facet Natalia Nenasheva
Clara Pitzschel
Cynthia N. Webster
Alexander J. Hart
Jill L. Wegrzyn
Mia M. Bengtsson
Katharina J. Hoff
author_sort Natalia Nenasheva
collection DOAJ
description Abstract Diatoms, a major group of microalgae, play a critical role in global carbon cycling and primary production. Despite their ecological significance, comprehensive genomic resources for diatoms are limited. To address this, we have annotated previously unannotated genome assemblies of 49 diatom species. Genome assemblies were obtained from NCBI Datasets and processed for repeat elements using RepeatModeler2 and RepeatMasker. For gene prediction, BRAKER2 was employed in the absence of transcriptomic data, while BRAKER3 was utilised when transcriptome short read data were available from the Sequence Read Archive. The quality of genome assemblies and predicted protein sets was evaluated using BUSCO, ensuring high-quality genomic resources. Functional annotation was performed using EnTAP, providing insights into the biological roles of the predicted proteins. Our study enhances the genomic toolkit available for diatoms, facilitating future research in diatom biology, ecology, and evolution.
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institution Kabale University
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spelling doaj-art-34928713c60241a99d561ea8fd8406072025-08-20T03:45:11ZengNature PortfolioScientific Data2052-44632025-06-0112111910.1038/s41597-025-05306-zAnnotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta cladeNatalia Nenasheva0Clara Pitzschel1Cynthia N. Webster2Alexander J. Hart3Jill L. Wegrzyn4Mia M. Bengtsson5Katharina J. Hoff6University of Greifswald, Institute of Mathematics and Computer Science and Center for Functional Genomics of MicrobesUniversity of Greifswald, Institute of Mathematics and Computer Science and Center for Functional Genomics of MicrobesUniversity of Connecticut, Department of Ecology and Evolutionary Biology, Plant Computational Genomics Lab, 75 N. Eagleville Road, Unit 3043University of Connecticut, Department of Ecology and Evolutionary Biology, Plant Computational Genomics Lab, 75 N. Eagleville Road, Unit 3043University of Connecticut, Department of Ecology and Evolutionary Biology, Plant Computational Genomics Lab, 75 N. Eagleville Road, Unit 3043University of Greifswald, Institute of Microbiology, Felix-Hausdorff-Straße 8University of Greifswald, Institute of Mathematics and Computer Science and Center for Functional Genomics of MicrobesAbstract Diatoms, a major group of microalgae, play a critical role in global carbon cycling and primary production. Despite their ecological significance, comprehensive genomic resources for diatoms are limited. To address this, we have annotated previously unannotated genome assemblies of 49 diatom species. Genome assemblies were obtained from NCBI Datasets and processed for repeat elements using RepeatModeler2 and RepeatMasker. For gene prediction, BRAKER2 was employed in the absence of transcriptomic data, while BRAKER3 was utilised when transcriptome short read data were available from the Sequence Read Archive. The quality of genome assemblies and predicted protein sets was evaluated using BUSCO, ensuring high-quality genomic resources. Functional annotation was performed using EnTAP, providing insights into the biological roles of the predicted proteins. Our study enhances the genomic toolkit available for diatoms, facilitating future research in diatom biology, ecology, and evolution.https://doi.org/10.1038/s41597-025-05306-z
spellingShingle Natalia Nenasheva
Clara Pitzschel
Cynthia N. Webster
Alexander J. Hart
Jill L. Wegrzyn
Mia M. Bengtsson
Katharina J. Hoff
Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade
Scientific Data
title Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade
title_full Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade
title_fullStr Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade
title_full_unstemmed Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade
title_short Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade
title_sort annotation of protein coding genes in 49 diatom genomes from the bacillariophyta clade
url https://doi.org/10.1038/s41597-025-05306-z
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