Fluorine-18-Labeled Positron Emission Tomography Probe Targeting Activated p38α: Design, Synthesis, and In Vivo Evaluation in Rodents

Fluorine-18-Labeled Positron Emission Tomography Probe Targeting Activated p38α: Design, Synthesis, and In Vivo Evaluation in Rodents

<b>Background/Objectives:</b> The kinase p38α, a member of the mitogen-activated protein kinase (MAPK) family, is activated by external stimuli and plays a crucial role in inflammation, tumor growth, and metabolic disorders. In particular, p38α is involved in thermogenesis and the metabo...

Full description

Saved in:
Bibliographic Details
Main Authors: Mikiya Futatsugi, Anna Miyazaki, Yasukazu Kanai, Naoya Kondo, Takashi Temma
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceuticals
Subjects:
p38α
brown adipose tissue
positron emission tomography
<sup>18</sup>F fluorination
molecular imaging
diabetes
Online Access:https://www.mdpi.com/1424-8247/18/4/600
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items