Current and Emerging Approaches for Hepatic Fibrosis Treatment
Liver fibrosis resulting from chronic liver injury is a key factor to develop liver cirrhosis and risk of hepatocellular carcinoma (HCC) which are major health burden worldwide. Therefore, it is necessary for antifibrotic therapies to prevent chronic liver disease progression and HCC development. Th...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2021/6612892 |
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| _version_ | 1850157590302949376 |
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| author | Jingguo Li Biguang Tuo |
| author_facet | Jingguo Li Biguang Tuo |
| author_sort | Jingguo Li |
| collection | DOAJ |
| description | Liver fibrosis resulting from chronic liver injury is a key factor to develop liver cirrhosis and risk of hepatocellular carcinoma (HCC) which are major health burden worldwide. Therefore, it is necessary for antifibrotic therapies to prevent chronic liver disease progression and HCC development. There has been tremendous progress in understanding the mechanisms of liver fibrosis in the last decade, which has created new opportunities for the treatment of this condition. In this review, we aim to make an overview on information of different potential therapies (drug treatment, cell therapy, and liver transplantation) for the liver fibrosis and hope to provide the therapeutic options available for the treatment of liver fibrosis and discuss novel approaches. |
| format | Article |
| id | doaj-art-3486829eb8b44f35aef3e85e4f0c7405 |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-3486829eb8b44f35aef3e85e4f0c74052025-08-20T02:24:07ZengWileyGastroenterology Research and Practice1687-61211687-630X2021-01-01202110.1155/2021/66128926612892Current and Emerging Approaches for Hepatic Fibrosis TreatmentJingguo Li0Biguang Tuo1Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaLiver fibrosis resulting from chronic liver injury is a key factor to develop liver cirrhosis and risk of hepatocellular carcinoma (HCC) which are major health burden worldwide. Therefore, it is necessary for antifibrotic therapies to prevent chronic liver disease progression and HCC development. There has been tremendous progress in understanding the mechanisms of liver fibrosis in the last decade, which has created new opportunities for the treatment of this condition. In this review, we aim to make an overview on information of different potential therapies (drug treatment, cell therapy, and liver transplantation) for the liver fibrosis and hope to provide the therapeutic options available for the treatment of liver fibrosis and discuss novel approaches.http://dx.doi.org/10.1155/2021/6612892 |
| spellingShingle | Jingguo Li Biguang Tuo Current and Emerging Approaches for Hepatic Fibrosis Treatment Gastroenterology Research and Practice |
| title | Current and Emerging Approaches for Hepatic Fibrosis Treatment |
| title_full | Current and Emerging Approaches for Hepatic Fibrosis Treatment |
| title_fullStr | Current and Emerging Approaches for Hepatic Fibrosis Treatment |
| title_full_unstemmed | Current and Emerging Approaches for Hepatic Fibrosis Treatment |
| title_short | Current and Emerging Approaches for Hepatic Fibrosis Treatment |
| title_sort | current and emerging approaches for hepatic fibrosis treatment |
| url | http://dx.doi.org/10.1155/2021/6612892 |
| work_keys_str_mv | AT jingguoli currentandemergingapproachesforhepaticfibrosistreatment AT biguangtuo currentandemergingapproachesforhepaticfibrosistreatment |