Limosilactobacillus reuteri SXDT-32-derived shikimic acid protects against colonic inflammation in piglets by inhibiting the PI3K-Akt pathway

Limosilactobacillus reuteri SXDT-32-derived shikimic acid protects against colonic inflammation in piglets by inhibiting the PI3K-Akt pathway

Abstract Background Colitis caused by bacterial infection is a major global health challenge. Unfortunately, current treatment options are limited. We previously disclosed that L. reuteri SXDT-32 was enriched in the feces of an ancient diarrhea-resistant pig breed (Mashen pig) in China over 2500 yea...

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Main Authors: Ying Chen, Chengzeng Luo, Zhaohan Zhan, Shuo Liu, Chunran Teng, Ruixiao Mao, Shunfen Zhang, Xunbozan Zhang, Qingshi Meng, Ruqing Zhong, Liang Chen, Hongfu Zhang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Intestinal inflammation
L. reuteri SXDT-32
PI3K-Akt pathway
Shikimic acid
Online Access:https://doi.org/10.1186/s40104-025-01221-w
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