The oxidative stress is typical peculiarity by multiple sclerosis
The problem of pathogenesis of multiple sclerosis is of great importance in modern neurology and its solution allows to determine a pathogenetic approach to treatment of this severe disease. Complex clinical-biochemical investigation has been conducted in 79 patients with multiple sclerosis and 75 m...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2008-12-01
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| Series: | Бюллетень сибирской медицины |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/3477 |
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| _version_ | 1849403526799687680 |
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| author | N. V. Krotenko V. M. Alifirova S. A. Ivanova |
| author_facet | N. V. Krotenko V. M. Alifirova S. A. Ivanova |
| author_sort | N. V. Krotenko |
| collection | DOAJ |
| description | The problem of pathogenesis of multiple sclerosis is of great importance in modern neurology and its solution allows to determine a pathogenetic approach to treatment of this severe disease. Complex clinical-biochemical investigation has been conducted in 79 patients with multiple sclerosis and 75 mentally and physically healthy persons. Parameters of intensification of lipid peroxidation and indices of the state of enzymatic and non-enzymatic patterns in antioxidant defense system in different clinical forms and at different stages of MS course have been analyzed. The data obtained confirm the presence of oxidant stress in the development of pathological process in MS. |
| format | Article |
| id | doaj-art-347bce2a05734c5cb85d52245c83a32b |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2008-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-347bce2a05734c5cb85d52245c83a32b2025-08-20T03:37:16ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842008-12-0175-120821310.20538/1682-0363-2008-5-1-208-2132123The oxidative stress is typical peculiarity by multiple sclerosisN. V. Krotenko0V. M. Alifirova1S. A. Ivanova2Сибирский государственный медицинский университетСибирский государственный медицинский университетНИИ психического здоровья ТНЦ СО РАМНThe problem of pathogenesis of multiple sclerosis is of great importance in modern neurology and its solution allows to determine a pathogenetic approach to treatment of this severe disease. Complex clinical-biochemical investigation has been conducted in 79 patients with multiple sclerosis and 75 mentally and physically healthy persons. Parameters of intensification of lipid peroxidation and indices of the state of enzymatic and non-enzymatic patterns in antioxidant defense system in different clinical forms and at different stages of MS course have been analyzed. The data obtained confirm the presence of oxidant stress in the development of pathological process in MS.https://bulletin.ssmu.ru/jour/article/view/3477 |
| spellingShingle | N. V. Krotenko V. M. Alifirova S. A. Ivanova The oxidative stress is typical peculiarity by multiple sclerosis Бюллетень сибирской медицины |
| title | The oxidative stress is typical peculiarity by multiple sclerosis |
| title_full | The oxidative stress is typical peculiarity by multiple sclerosis |
| title_fullStr | The oxidative stress is typical peculiarity by multiple sclerosis |
| title_full_unstemmed | The oxidative stress is typical peculiarity by multiple sclerosis |
| title_short | The oxidative stress is typical peculiarity by multiple sclerosis |
| title_sort | oxidative stress is typical peculiarity by multiple sclerosis |
| url | https://bulletin.ssmu.ru/jour/article/view/3477 |
| work_keys_str_mv | AT nvkrotenko theoxidativestressistypicalpeculiaritybymultiplesclerosis AT vmalifirova theoxidativestressistypicalpeculiaritybymultiplesclerosis AT saivanova theoxidativestressistypicalpeculiaritybymultiplesclerosis AT nvkrotenko oxidativestressistypicalpeculiaritybymultiplesclerosis AT vmalifirova oxidativestressistypicalpeculiaritybymultiplesclerosis AT saivanova oxidativestressistypicalpeculiaritybymultiplesclerosis |