Targeted and Non-Targeted Metabolomic Evaluation of Cerebrospinal Fluid in Early Phase Schizophrenia: A Pilot Study from the Hopkins First Episode Psychosis Project

Targeted and Non-Targeted Metabolomic Evaluation of Cerebrospinal Fluid in Early Phase Schizophrenia: A Pilot Study from the Hopkins First Episode Psychosis Project

(1) Background: The lack of reliable biomarkers remains a significant barrier to improving outcomes for patients with schizophrenia. While metabolomic analyses of blood, urine, and feces have been explored, results have been inconsistent. Compared to peripheral compartments, cerebrospinal fluid (CSF...

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Main Authors: George E. Jaskiw, Mark E. Obrenovich, Curtis J. Donskey, Farren B. S. Briggs, Sun Sunnie Chung, Anastasiya I. Kalinina, Austin Bolomey, Lindsay N. Hayes, Kun Yang, Robert H. Yolken, Akira Sawa
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Metabolites
Subjects:
metabolome
cerebrospinal fluid
first-episode psychosis
schizophrenia
biomarker
gut microbiome
Online Access:https://www.mdpi.com/2218-1989/15/4/275
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