Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a Dog
ABSTRACT A 7‐year‐old neutered female Shih Tzu presented with bilateral skin lesions and a subcutaneous mass in the submandibular region. The initial lesion on the right appeared as a plaque, followed by the development of an ulcer on the opposite side 2–3 days later. Despite treatment with antibiot...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-05-01
|
| Series: | Veterinary Medicine and Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/vms3.70327 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850139796150681600 |
|---|---|
| author | Sungjae Lee Jooyoung Park Yeon Chae Hakhyun Kim Taesik Yun Byeong‐Teck Kang |
| author_facet | Sungjae Lee Jooyoung Park Yeon Chae Hakhyun Kim Taesik Yun Byeong‐Teck Kang |
| author_sort | Sungjae Lee |
| collection | DOAJ |
| description | ABSTRACT A 7‐year‐old neutered female Shih Tzu presented with bilateral skin lesions and a subcutaneous mass in the submandibular region. The initial lesion on the right appeared as a plaque, followed by the development of an ulcer on the opposite side 2–3 days later. Despite treatment with antibiotics, antifungal drugs and anti‐inflammatory steroids, lesions persisted. There was an initial improvement with steroids; however, the lesions developed into scars, erythema and papules. A biopsy revealed eosinophilic and mixed‐cell dermatitis requiring treatment with immunosuppressive steroids and cyclosporine, which resolved the plaque and ulcer but only partially reduced the subcutaneous mass. Surgical resection was considered, and subsequent skull radiography revealed alveolar bone loss. During surgery, a sinus tract was identified extending from teeth 309 to 409, indicating that the tissue changes were likely due to drainage from the periodontal disease. Based on clinical history and examination results, the case was definitively diagnosed as an odontogenic cutaneous sinus tract (OCST). Following surgery, no recurrence of the lesion or mass was observed. This is the first case report describing the histopathological features of a submandibular OCST in a dog, highlighting the importance of considering this condition when submandibular lesions do not fully respond to immunosuppressive therapy. |
| format | Article |
| id | doaj-art-3464eced4cfd4862b2d55dd3b3b0e76a |
| institution | OA Journals |
| issn | 2053-1095 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine and Science |
| spelling | doaj-art-3464eced4cfd4862b2d55dd3b3b0e76a2025-08-20T02:30:06ZengWileyVeterinary Medicine and Science2053-10952025-05-01113n/an/a10.1002/vms3.70327Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a DogSungjae Lee0Jooyoung Park1Yeon Chae2Hakhyun Kim3Taesik Yun4Byeong‐Teck Kang5Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungcheongbuk Republic of South KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungcheongbuk Republic of South KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungcheongbuk Republic of South KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungcheongbuk Republic of South KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungcheongbuk Republic of South KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungcheongbuk Republic of South KoreaABSTRACT A 7‐year‐old neutered female Shih Tzu presented with bilateral skin lesions and a subcutaneous mass in the submandibular region. The initial lesion on the right appeared as a plaque, followed by the development of an ulcer on the opposite side 2–3 days later. Despite treatment with antibiotics, antifungal drugs and anti‐inflammatory steroids, lesions persisted. There was an initial improvement with steroids; however, the lesions developed into scars, erythema and papules. A biopsy revealed eosinophilic and mixed‐cell dermatitis requiring treatment with immunosuppressive steroids and cyclosporine, which resolved the plaque and ulcer but only partially reduced the subcutaneous mass. Surgical resection was considered, and subsequent skull radiography revealed alveolar bone loss. During surgery, a sinus tract was identified extending from teeth 309 to 409, indicating that the tissue changes were likely due to drainage from the periodontal disease. Based on clinical history and examination results, the case was definitively diagnosed as an odontogenic cutaneous sinus tract (OCST). Following surgery, no recurrence of the lesion or mass was observed. This is the first case report describing the histopathological features of a submandibular OCST in a dog, highlighting the importance of considering this condition when submandibular lesions do not fully respond to immunosuppressive therapy.https://doi.org/10.1002/vms3.70327eosinophilic and mixed‐cell dermatitisgranulomaimmunosuppressive therapyodontogenic cutaneous sinus tract |
| spellingShingle | Sungjae Lee Jooyoung Park Yeon Chae Hakhyun Kim Taesik Yun Byeong‐Teck Kang Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a Dog Veterinary Medicine and Science eosinophilic and mixed‐cell dermatitis granuloma immunosuppressive therapy odontogenic cutaneous sinus tract |
| title | Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a Dog |
| title_full | Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a Dog |
| title_fullStr | Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a Dog |
| title_full_unstemmed | Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a Dog |
| title_short | Eosinophilic and Mixed‐Cell Infiltration in Odontogenic Cutaneous Sinus Tracts of a Dog |
| title_sort | eosinophilic and mixed cell infiltration in odontogenic cutaneous sinus tracts of a dog |
| topic | eosinophilic and mixed‐cell dermatitis granuloma immunosuppressive therapy odontogenic cutaneous sinus tract |
| url | https://doi.org/10.1002/vms3.70327 |
| work_keys_str_mv | AT sungjaelee eosinophilicandmixedcellinfiltrationinodontogeniccutaneoussinustractsofadog AT jooyoungpark eosinophilicandmixedcellinfiltrationinodontogeniccutaneoussinustractsofadog AT yeonchae eosinophilicandmixedcellinfiltrationinodontogeniccutaneoussinustractsofadog AT hakhyunkim eosinophilicandmixedcellinfiltrationinodontogeniccutaneoussinustractsofadog AT taesikyun eosinophilicandmixedcellinfiltrationinodontogeniccutaneoussinustractsofadog AT byeongteckkang eosinophilicandmixedcellinfiltrationinodontogeniccutaneoussinustractsofadog |