The anionic surfactant Sodium Dodecyl Benzene Sulfonate alleviates inflammatory responses in atopic dermatitis via NFκB/MAPK pathways in a STAT3-dependent manner

The anionic surfactant Sodium Dodecyl Benzene Sulfonate alleviates inflammatory responses in atopic dermatitis via NFκB/MAPK pathways in a STAT3-dependent manner

Abstract Atopic dermatitis (AD) is a common chronic inflammatory skin disease characterized by chronic inflammation, barrier impairment, and immunoglobulin E-mediated sensitization. Sodium dodecyl benzene sulfonate (SDBS) is a widely used anionic surfactant which are believed to exacerbate AD accord...

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Main Authors: Han Zhang, Zizhuo Li, Zhanglei Mu, You Wu, Suli Zhang, Yaguang Zhou, Dongdong Zhang, Xiaojing Zhao, Weiwei Xing, Yanan Wang, Biwen Lin, Xiaoqiang Liang, Chunfu Zheng, Chengxin Li, Jianzhong Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Atopic dermatitis
Sodium Dodecyl benzene sulfonate
Surfactants
Online Access:https://doi.org/10.1038/s41598-025-12776-z
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