Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping review
We present four cases of male genital schistosomiasis (MGS) within children and adolescents opportunistically encountered as part of a wider screening programme for imported schistosomiasis in Germany and community outreach screening in Mali. Such genital manifestations in young children and adolesc...
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| Series: | Parasitology |
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| author | Joachim Richter Sekeleghe A. Kayuni J. Russell Stothard Charles Émile Ramarokoto Andreas K. Lindner Daniela Fusco Hermann Feldmeier Amaya L. Bustinduy Jennifer F. Friedman |
| author_facet | Joachim Richter Sekeleghe A. Kayuni J. Russell Stothard Charles Émile Ramarokoto Andreas K. Lindner Daniela Fusco Hermann Feldmeier Amaya L. Bustinduy Jennifer F. Friedman |
| author_sort | Joachim Richter |
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| description | We present four cases of male genital schistosomiasis (MGS) within children and adolescents opportunistically encountered as part of a wider screening programme for imported schistosomiasis in Germany and community outreach screening in Mali. Such genital manifestations in young children and adolescents are often overlooked but can include hydrocele, hypogonadism, varicocele, cutaneous granulomata on the penis and scrotum, echogenic spots in the prostate and the epididymis, alongside testicular masses. Though these cases appear sporadic, from our scoping literature review, they draw fresh attention on MGS in young children and highlight wider confusion with other congenital, neoplastic and infectious disease. These might include an insufficient closure of the tunica vaginalis, malignancies or lymphatic filariasis. Frequently haematuria is not present. One typical sign indicating MGS in adults, i.e. haematospermia is not present before puberty. Another reason of missing MGS cases may be that screening with scrotal or transabdominal ultrasonography are not easily accepted unless the reason for it is not extensively explained beforehand and that transabdominal ultrasonography is less sensitive for revealing prostatic lesions than transrectal ultrasonography. |
| format | Article |
| id | doaj-art-345e9d62dc0f47b09d3b074a6771f410 |
| institution | DOAJ |
| issn | 0031-1820 1469-8161 |
| language | English |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Parasitology |
| spelling | doaj-art-345e9d62dc0f47b09d3b074a6771f4102025-08-20T03:02:47ZengCambridge University PressParasitology0031-18201469-816111010.1017/S0031182025000241Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping reviewJoachim Richter0https://orcid.org/0000-0002-1930-2944Sekeleghe A. Kayuni1J. Russell Stothard2https://orcid.org/0000-0002-9370-3420Charles Émile Ramarokoto3Andreas K. Lindner4Daniela Fusco5Hermann Feldmeier6Amaya L. Bustinduy7https://orcid.org/0000-0001-6131-4159Jennifer F. Friedman8Institute of International Health, Global Health Center, Charité Universitätsmedizin, Corporate Member of Free University and Humboldt University and Berlin Institute of Health, Berlin, Germany Centre for Tropical and Travel Medicine, Swiss Tropical and Public Health Institute, Basel, SwitzerlandDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UKDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UKEpidemiology Unit, Institut Pasteur, Antananarivo, MadagascarInstitute of International Health, Global Health Center, Charité Universitätsmedizin, Corporate Member of Free University and Humboldt University and Berlin Institute of Health, Berlin, GermanyImplementation Research Group, Bernhard Nocht Institute for Tropical Medicine, Hamburg, GermanyInstitute of Microbiology, Charité Universitätsmedizin, Corporate Member of Free University and Humboldt University and Berlin Institute of Health, Berlin, GermanyDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UKLifespan Center for International Health Research (CIHR), Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, USAWe present four cases of male genital schistosomiasis (MGS) within children and adolescents opportunistically encountered as part of a wider screening programme for imported schistosomiasis in Germany and community outreach screening in Mali. Such genital manifestations in young children and adolescents are often overlooked but can include hydrocele, hypogonadism, varicocele, cutaneous granulomata on the penis and scrotum, echogenic spots in the prostate and the epididymis, alongside testicular masses. Though these cases appear sporadic, from our scoping literature review, they draw fresh attention on MGS in young children and highlight wider confusion with other congenital, neoplastic and infectious disease. These might include an insufficient closure of the tunica vaginalis, malignancies or lymphatic filariasis. Frequently haematuria is not present. One typical sign indicating MGS in adults, i.e. haematospermia is not present before puberty. Another reason of missing MGS cases may be that screening with scrotal or transabdominal ultrasonography are not easily accepted unless the reason for it is not extensively explained beforehand and that transabdominal ultrasonography is less sensitive for revealing prostatic lesions than transrectal ultrasonography.https://www.cambridge.org/core/product/identifier/S0031182025000241/type/journal_articleadolescentschildrenhydrocelehypogonadismmale genital schistosomiasisminorsSchistosomaschistosomiasistesticular massesultrasound |
| spellingShingle | Joachim Richter Sekeleghe A. Kayuni J. Russell Stothard Charles Émile Ramarokoto Andreas K. Lindner Daniela Fusco Hermann Feldmeier Amaya L. Bustinduy Jennifer F. Friedman Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping review Parasitology adolescents children hydrocele hypogonadism male genital schistosomiasis minors Schistosoma schistosomiasis testicular masses ultrasound |
| title | Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping review |
| title_full | Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping review |
| title_fullStr | Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping review |
| title_full_unstemmed | Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping review |
| title_short | Description of four cases of male genital schistosomiasis (MGS) in children and adolescents, with a scoping review |
| title_sort | description of four cases of male genital schistosomiasis mgs in children and adolescents with a scoping review |
| topic | adolescents children hydrocele hypogonadism male genital schistosomiasis minors Schistosoma schistosomiasis testicular masses ultrasound |
| url | https://www.cambridge.org/core/product/identifier/S0031182025000241/type/journal_article |
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