Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis

Antibiotic prophylaxis in children with vesicoureteral reflux (VUR) remains controversial. We reviewed patients diagnosed with VUR after an index urinary tract infection (UTI) who subsequently received antibiotic prophylaxis. Recurrent UTIs in patients with and without urologic anomalies occurred in...

Full description

Saved in:
Bibliographic Details
Main Authors: Madeline G Tompkins, Michelle Kussin, John C Christenson, LaKeisha Boyd, Kiet Tat, Jack G Schneider, Rachel T Han
Format: Article
Language:English
Published: Cambridge University Press 2025-01-01
Series:Antimicrobial Stewardship & Healthcare Epidemiology
Online Access:https://www.cambridge.org/core/product/identifier/S2732494X24004972/type/journal_article
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823856410087129088
author Madeline G Tompkins
Michelle Kussin
John C Christenson
LaKeisha Boyd
Kiet Tat
Jack G Schneider
Rachel T Han
author_facet Madeline G Tompkins
Michelle Kussin
John C Christenson
LaKeisha Boyd
Kiet Tat
Jack G Schneider
Rachel T Han
author_sort Madeline G Tompkins
collection DOAJ
description Antibiotic prophylaxis in children with vesicoureteral reflux (VUR) remains controversial. We reviewed patients diagnosed with VUR after an index urinary tract infection (UTI) who subsequently received antibiotic prophylaxis. Recurrent UTIs in patients with and without urologic anomalies occurred in 57% and 33%, respectively. Multidrug-resistant organisms accounted for 25% of first UTI recurrences.
format Article
id doaj-art-3459c35180f748e4ba669a4f0ae7a396
institution Kabale University
issn 2732-494X
language English
publishDate 2025-01-01
publisher Cambridge University Press
record_format Article
series Antimicrobial Stewardship & Healthcare Epidemiology
spelling doaj-art-3459c35180f748e4ba669a4f0ae7a3962025-02-12T08:41:43ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2025-01-01510.1017/ash.2024.497Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxisMadeline G Tompkins0Michelle Kussin1John C Christenson2LaKeisha Boyd3https://orcid.org/0000-0003-3549-2124Kiet Tat4Jack G Schneider5https://orcid.org/0000-0002-2838-7644Rachel T Han6https://orcid.org/0000-0001-5409-3431Department of Pharmacy, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USADepartment of Pharmacy, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA Ryan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USARyan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USADepartment of Biostatistics and Health Data Science, Indiana University School of Medicine and Richard M. Fairbanks School of Public Health, Indianapolis, IN, USAIndiana University School of Medicine, Indianapolis, IN, USARyan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USADivision of Neonatology, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USAAntibiotic prophylaxis in children with vesicoureteral reflux (VUR) remains controversial. We reviewed patients diagnosed with VUR after an index urinary tract infection (UTI) who subsequently received antibiotic prophylaxis. Recurrent UTIs in patients with and without urologic anomalies occurred in 57% and 33%, respectively. Multidrug-resistant organisms accounted for 25% of first UTI recurrences.https://www.cambridge.org/core/product/identifier/S2732494X24004972/type/journal_article
spellingShingle Madeline G Tompkins
Michelle Kussin
John C Christenson
LaKeisha Boyd
Kiet Tat
Jack G Schneider
Rachel T Han
Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
Antimicrobial Stewardship & Healthcare Epidemiology
title Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
title_full Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
title_fullStr Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
title_full_unstemmed Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
title_short Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
title_sort outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
url https://www.cambridge.org/core/product/identifier/S2732494X24004972/type/journal_article
work_keys_str_mv AT madelinegtompkins outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis
AT michellekussin outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis
AT johncchristenson outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis
AT lakeishaboyd outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis
AT kiettat outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis
AT jackgschneider outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis
AT rachelthan outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis