Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis
Antibiotic prophylaxis in children with vesicoureteral reflux (VUR) remains controversial. We reviewed patients diagnosed with VUR after an index urinary tract infection (UTI) who subsequently received antibiotic prophylaxis. Recurrent UTIs in patients with and without urologic anomalies occurred in...
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Format: | Article |
Language: | English |
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Cambridge University Press
2025-01-01
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Series: | Antimicrobial Stewardship & Healthcare Epidemiology |
Online Access: | https://www.cambridge.org/core/product/identifier/S2732494X24004972/type/journal_article |
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author | Madeline G Tompkins Michelle Kussin John C Christenson LaKeisha Boyd Kiet Tat Jack G Schneider Rachel T Han |
author_facet | Madeline G Tompkins Michelle Kussin John C Christenson LaKeisha Boyd Kiet Tat Jack G Schneider Rachel T Han |
author_sort | Madeline G Tompkins |
collection | DOAJ |
description | Antibiotic prophylaxis in children with vesicoureteral reflux (VUR) remains controversial. We reviewed patients diagnosed with VUR after an index urinary tract infection (UTI) who subsequently received antibiotic prophylaxis. Recurrent UTIs in patients with and without urologic anomalies occurred in 57% and 33%, respectively. Multidrug-resistant organisms accounted for 25% of first UTI recurrences. |
format | Article |
id | doaj-art-3459c35180f748e4ba669a4f0ae7a396 |
institution | Kabale University |
issn | 2732-494X |
language | English |
publishDate | 2025-01-01 |
publisher | Cambridge University Press |
record_format | Article |
series | Antimicrobial Stewardship & Healthcare Epidemiology |
spelling | doaj-art-3459c35180f748e4ba669a4f0ae7a3962025-02-12T08:41:43ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2025-01-01510.1017/ash.2024.497Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxisMadeline G Tompkins0Michelle Kussin1John C Christenson2LaKeisha Boyd3https://orcid.org/0000-0003-3549-2124Kiet Tat4Jack G Schneider5https://orcid.org/0000-0002-2838-7644Rachel T Han6https://orcid.org/0000-0001-5409-3431Department of Pharmacy, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USADepartment of Pharmacy, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA Ryan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USARyan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USADepartment of Biostatistics and Health Data Science, Indiana University School of Medicine and Richard M. Fairbanks School of Public Health, Indianapolis, IN, USAIndiana University School of Medicine, Indianapolis, IN, USARyan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USADivision of Neonatology, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USAAntibiotic prophylaxis in children with vesicoureteral reflux (VUR) remains controversial. We reviewed patients diagnosed with VUR after an index urinary tract infection (UTI) who subsequently received antibiotic prophylaxis. Recurrent UTIs in patients with and without urologic anomalies occurred in 57% and 33%, respectively. Multidrug-resistant organisms accounted for 25% of first UTI recurrences.https://www.cambridge.org/core/product/identifier/S2732494X24004972/type/journal_article |
spellingShingle | Madeline G Tompkins Michelle Kussin John C Christenson LaKeisha Boyd Kiet Tat Jack G Schneider Rachel T Han Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis Antimicrobial Stewardship & Healthcare Epidemiology |
title | Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis |
title_full | Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis |
title_fullStr | Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis |
title_full_unstemmed | Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis |
title_short | Outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis |
title_sort | outcomes in children with vesicoureteral reflux receiving antibiotic prophylaxis |
url | https://www.cambridge.org/core/product/identifier/S2732494X24004972/type/journal_article |
work_keys_str_mv | AT madelinegtompkins outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis AT michellekussin outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis AT johncchristenson outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis AT lakeishaboyd outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis AT kiettat outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis AT jackgschneider outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis AT rachelthan outcomesinchildrenwithvesicoureteralrefluxreceivingantibioticprophylaxis |