Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases
The growing global elderly population underscores the escalating importance of anti-aging interventions to combat age-related diseases and extend both health span and lifespan. Over the past decades, various anti-aging interventions have gained recognition, each with its unique set of advantages and...
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MDPI AG
2025-07-01
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| author | An Yu Changguo Ma Min Hu |
| author_facet | An Yu Changguo Ma Min Hu |
| author_sort | An Yu |
| collection | DOAJ |
| description | The growing global elderly population underscores the escalating importance of anti-aging interventions to combat age-related diseases and extend both health span and lifespan. Over the past decades, various anti-aging interventions have gained recognition, each with its unique set of advantages and limitations. Notably, the transplantation of rejuvenated autologous adult stem cells is standing out as a powerful strategy that holds significant promise in combating age-related functional decline and diseases. This review delves into our current biological insights into cellular rejuvenation and provides an overview of both pre-clinical and clinical experiences with autologous and allogeneic adult stem cell transplantations. It reinforces the concept that rejuvenated adult stem cells constitute a pivotal element in the quest for the fountain of youth. Additionally, we examine the technical challenges involved in obtaining and utilizing these rejuvenated adult stem cells. |
| format | Article |
| id | doaj-art-3454d756111048df981066d495172dfa |
| institution | Kabale University |
| issn | 2073-4409 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj-art-3454d756111048df981066d495172dfa2025-08-20T04:00:54ZengMDPI AGCells2073-44092025-07-011415115310.3390/cells14151153Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated DiseasesAn Yu0Changguo Ma1Min Hu2Yunnan Key Laboratory of Cell Therapy for Refractory Diseases, Kunming University, Kunming 650214, ChinaYunnan Key Laboratory of Cell Therapy for Refractory Diseases, Kunming University, Kunming 650214, ChinaYunnan Key Laboratory of Cell Therapy for Refractory Diseases, Kunming University, Kunming 650214, ChinaThe growing global elderly population underscores the escalating importance of anti-aging interventions to combat age-related diseases and extend both health span and lifespan. Over the past decades, various anti-aging interventions have gained recognition, each with its unique set of advantages and limitations. Notably, the transplantation of rejuvenated autologous adult stem cells is standing out as a powerful strategy that holds significant promise in combating age-related functional decline and diseases. This review delves into our current biological insights into cellular rejuvenation and provides an overview of both pre-clinical and clinical experiences with autologous and allogeneic adult stem cell transplantations. It reinforces the concept that rejuvenated adult stem cells constitute a pivotal element in the quest for the fountain of youth. Additionally, we examine the technical challenges involved in obtaining and utilizing these rejuvenated adult stem cells.https://www.mdpi.com/2073-4409/14/15/1153adult stem cellsautologous transplantationcellular rejuvenationcellular reprogramming |
| spellingShingle | An Yu Changguo Ma Min Hu Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases Cells adult stem cells autologous transplantation cellular rejuvenation cellular reprogramming |
| title | Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases |
| title_full | Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases |
| title_fullStr | Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases |
| title_full_unstemmed | Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases |
| title_short | Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases |
| title_sort | rejuvenated autologous adult stem cells emerging front runners in the fight against aging and associated diseases |
| topic | adult stem cells autologous transplantation cellular rejuvenation cellular reprogramming |
| url | https://www.mdpi.com/2073-4409/14/15/1153 |
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