Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient
Methicillin-resistant Staphylococcus aureus (MRSA) is a common nosocomial infection that has a high burden of morbidity and mortality. Vancomycin is the often-used antibiotic of choice when MRSA is suspected as a causative infectious agent. Recent studies have called into question the reliability of...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2015/175810 |
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| _version_ | 1832554625459290112 |
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| author | David Benjamin Lash Jeremiah Joson Arash Heidari |
| author_facet | David Benjamin Lash Jeremiah Joson Arash Heidari |
| author_sort | David Benjamin Lash |
| collection | DOAJ |
| description | Methicillin-resistant Staphylococcus aureus (MRSA) is a common nosocomial infection that has a high burden of morbidity and mortality. Vancomycin is the often-used antibiotic of choice when MRSA is suspected as a causative infectious agent. Recent studies have called into question the reliability of vancomycin as empiric therapy, especially in instances of bacteremia. The isolate’s minimum inhibitory concentration (MIC), the source of infection, modality of susceptibility testing, and antibiotic resistance are all issues that should be taken into consideration when formulating a care plan for a patient. We present a case that illustrates some of these issues clinicians are facing. |
| format | Article |
| id | doaj-art-344e8e8f9cc5439685ec0e222b9dad67 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-344e8e8f9cc5439685ec0e222b9dad672025-02-03T05:51:03ZengWileyCase Reports in Infectious Diseases2090-66252090-66332015-01-01201510.1155/2015/175810175810Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis PatientDavid Benjamin Lash0Jeremiah Joson1Arash Heidari2Department of Pharmacy, Kern Medical Center, Bakersfield, CA 93306, USADepartment of Pharmacy, Kern Medical Center, Bakersfield, CA 93306, USADepartment of Medicine, Kern Medical Center, Bakersfield, CA 93306, USAMethicillin-resistant Staphylococcus aureus (MRSA) is a common nosocomial infection that has a high burden of morbidity and mortality. Vancomycin is the often-used antibiotic of choice when MRSA is suspected as a causative infectious agent. Recent studies have called into question the reliability of vancomycin as empiric therapy, especially in instances of bacteremia. The isolate’s minimum inhibitory concentration (MIC), the source of infection, modality of susceptibility testing, and antibiotic resistance are all issues that should be taken into consideration when formulating a care plan for a patient. We present a case that illustrates some of these issues clinicians are facing.http://dx.doi.org/10.1155/2015/175810 |
| spellingShingle | David Benjamin Lash Jeremiah Joson Arash Heidari Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient Case Reports in Infectious Diseases |
| title | Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient |
| title_full | Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient |
| title_fullStr | Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient |
| title_full_unstemmed | Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient |
| title_short | Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient |
| title_sort | differences in method specific vancomycin mics and induced daptomycin resistance in an infective endocarditis patient |
| url | http://dx.doi.org/10.1155/2015/175810 |
| work_keys_str_mv | AT davidbenjaminlash differencesinmethodspecificvancomycinmicsandinduceddaptomycinresistanceinaninfectiveendocarditispatient AT jeremiahjoson differencesinmethodspecificvancomycinmicsandinduceddaptomycinresistanceinaninfectiveendocarditispatient AT arashheidari differencesinmethodspecificvancomycinmicsandinduceddaptomycinresistanceinaninfectiveendocarditispatient |