Research progress of spatial transcriptomics and its applications in bone research
The structural and functional heterogeneity of cells in bone tissue is closely related to their spatial location. Spatial transcriptomics can simultaneously obtain location information and transcriptome changes of spatial units within tissues. In recent years, the rapid development of spatial transc...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Oral and Maxillofacial Surgery
2024-04-01
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| Series: | Kouqiang hemian waike zazhi |
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| Online Access: | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.02.011 |
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| _version_ | 1849225090385838080 |
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| author | CHEN Yongliang WANG Zuolin |
| author_facet | CHEN Yongliang WANG Zuolin |
| author_sort | CHEN Yongliang |
| collection | DOAJ |
| description | The structural and functional heterogeneity of cells in bone tissue is closely related to their spatial location. Spatial transcriptomics can simultaneously obtain location information and transcriptome changes of spatial units within tissues. In recent years, the rapid development of spatial transcriptomics has enabled high-resolution and high-throughput transcriptome analysis of tissues and organs, and has been continuously applied in the study of the skeletal system. This article reviews the progress of spatial transcriptomics and its applications in bone research. |
| format | Article |
| id | doaj-art-3444d3d6c9cd4a64aa6ea49c269817aa |
| institution | Kabale University |
| issn | 1005-4979 |
| language | zho |
| publishDate | 2024-04-01 |
| publisher | Editorial Office of Journal of Oral and Maxillofacial Surgery |
| record_format | Article |
| series | Kouqiang hemian waike zazhi |
| spelling | doaj-art-3444d3d6c9cd4a64aa6ea49c269817aa2025-08-25T06:10:59ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792024-04-0134214314510.12439/kqhm.1005-4979.2024.02.011Research progress of spatial transcriptomics and its applications in bone researchCHEN Yongliang0WANG Zuolin1Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral Implantology, Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral Implantology, Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaThe structural and functional heterogeneity of cells in bone tissue is closely related to their spatial location. Spatial transcriptomics can simultaneously obtain location information and transcriptome changes of spatial units within tissues. In recent years, the rapid development of spatial transcriptomics has enabled high-resolution and high-throughput transcriptome analysis of tissues and organs, and has been continuously applied in the study of the skeletal system. This article reviews the progress of spatial transcriptomics and its applications in bone research.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.02.011spatial transcriptomicsnext generation sequencingbone marrow microenvironmentmesenchymal stem cell |
| spellingShingle | CHEN Yongliang WANG Zuolin Research progress of spatial transcriptomics and its applications in bone research Kouqiang hemian waike zazhi spatial transcriptomics next generation sequencing bone marrow microenvironment mesenchymal stem cell |
| title | Research progress of spatial transcriptomics and its applications in bone research |
| title_full | Research progress of spatial transcriptomics and its applications in bone research |
| title_fullStr | Research progress of spatial transcriptomics and its applications in bone research |
| title_full_unstemmed | Research progress of spatial transcriptomics and its applications in bone research |
| title_short | Research progress of spatial transcriptomics and its applications in bone research |
| title_sort | research progress of spatial transcriptomics and its applications in bone research |
| topic | spatial transcriptomics next generation sequencing bone marrow microenvironment mesenchymal stem cell |
| url | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.02.011 |
| work_keys_str_mv | AT chenyongliang researchprogressofspatialtranscriptomicsanditsapplicationsinboneresearch AT wangzuolin researchprogressofspatialtranscriptomicsanditsapplicationsinboneresearch |