Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review

Müllerian anomalies (MA) are structural defects that arise due to alterations in the development of the paramesonephric or Müllerian ducts during the first 16 weeks of gestation. Few cases have been reported on laparoscopic management as a diagnostic and therapeutic method in Müllerian anomalies. Th...

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Main Authors: Mario Riquelme, Juan Pelayo, Irving Cardenas-Medina, Ana Cantu-Zendejas, Alejandro Cendejas-Higuera, Eduardo Olazabal, Mario Palafox
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Journal of Pediatric Surgery Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949711625000127
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author Mario Riquelme
Juan Pelayo
Irving Cardenas-Medina
Ana Cantu-Zendejas
Alejandro Cendejas-Higuera
Eduardo Olazabal
Mario Palafox
author_facet Mario Riquelme
Juan Pelayo
Irving Cardenas-Medina
Ana Cantu-Zendejas
Alejandro Cendejas-Higuera
Eduardo Olazabal
Mario Palafox
author_sort Mario Riquelme
collection DOAJ
description Müllerian anomalies (MA) are structural defects that arise due to alterations in the development of the paramesonephric or Müllerian ducts during the first 16 weeks of gestation. Few cases have been reported on laparoscopic management as a diagnostic and therapeutic method in Müllerian anomalies. This study presents a retrospective case series of 9 patients diagnosed with Müllerian anomalies. A diagnostic approach was performed on 9 patients with suspected Müllerian anomalies, including 3 patients with OHVIRA Syndrome. Of all patients, 8 of them were treated with minimally invasive procedures, and one delayed the treatment. Our findings highlight the importance of employing advanced imaging techniques, such as MRI and UroCT, in complex cases to ensure accurate diagnosis and optimal surgical planning. Our case series demonstrates that most patients can have their condition successfully managed through a minimally invasive approach, as highlighted in the reported cases. Future studies should focus on expanding the clinical evidence base, focusing on long-term follow-up to assess fertility outcomes, quality of life and durability of these surgical interventions.
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spelling doaj-art-342f85b926cd49478d023c5fa047a52d2025-08-20T02:25:01ZengElsevierJournal of Pediatric Surgery Open2949-71162025-04-011010020310.1016/j.yjpso.2025.100203Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature reviewMario Riquelme0Juan Pelayo1Irving Cardenas-Medina2Ana Cantu-Zendejas3Alejandro Cendejas-Higuera4Eduardo Olazabal5Mario Palafox6Christus Muguerza Hospital, Monterrey, Nuevo Leon, Mexico; Corresponding author at: 15 de Mayo 1822-l, Maria Luisa, Nuevo Obispado, 64040 Monterrey, N.L, Mexico.Sinai Medical Center Guerin's Children, Los Angeles, CA, USAInstituto Mexicano del Seguro Social, Monterrey, Nuevo León, MexicoHospital Christus Muguerza, Monterrey, Nuevo Leon, MexicoHospital Christus Muguerza, Monterrey, Nuevo Leon, MexicoUniversity Hospital, Torreon, Coahuila, MexicoChildren Hospital, Puebla, MexicoMüllerian anomalies (MA) are structural defects that arise due to alterations in the development of the paramesonephric or Müllerian ducts during the first 16 weeks of gestation. Few cases have been reported on laparoscopic management as a diagnostic and therapeutic method in Müllerian anomalies. This study presents a retrospective case series of 9 patients diagnosed with Müllerian anomalies. A diagnostic approach was performed on 9 patients with suspected Müllerian anomalies, including 3 patients with OHVIRA Syndrome. Of all patients, 8 of them were treated with minimally invasive procedures, and one delayed the treatment. Our findings highlight the importance of employing advanced imaging techniques, such as MRI and UroCT, in complex cases to ensure accurate diagnosis and optimal surgical planning. Our case series demonstrates that most patients can have their condition successfully managed through a minimally invasive approach, as highlighted in the reported cases. Future studies should focus on expanding the clinical evidence base, focusing on long-term follow-up to assess fertility outcomes, quality of life and durability of these surgical interventions.http://www.sciencedirect.com/science/article/pii/S2949711625000127Müllerian anomaliesOhvira syndromeDidelphic uterusMinimally invasive surgeryObstructed hemivaginaMultiseptated transverse septum
spellingShingle Mario Riquelme
Juan Pelayo
Irving Cardenas-Medina
Ana Cantu-Zendejas
Alejandro Cendejas-Higuera
Eduardo Olazabal
Mario Palafox
Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review
Journal of Pediatric Surgery Open
Müllerian anomalies
Ohvira syndrome
Didelphic uterus
Minimally invasive surgery
Obstructed hemivagina
Multiseptated transverse septum
title Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review
title_full Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review
title_fullStr Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review
title_full_unstemmed Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review
title_short Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review
title_sort minimally invasive management of mullerian anomalies in pediatric patients a retrospective case series and literature review
topic Müllerian anomalies
Ohvira syndrome
Didelphic uterus
Minimally invasive surgery
Obstructed hemivagina
Multiseptated transverse septum
url http://www.sciencedirect.com/science/article/pii/S2949711625000127
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