Infantile Iatrogenic Cushing Syndrome due to Topical Steroids
Cushing syndrome is an endocrinological disorder characterized by increased free plasma glucocorticoids level. It is either due to an excessive endogenous release of steroids (e.g., pituitary adenoma or adrenal hyperplasia) or exogenous administration of steroids. In children, iatrogenic Cushing syn...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2019/2652961 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850157127488765952 |
|---|---|
| author | Lulwah Alkhuder Horia Mawlawi |
| author_facet | Lulwah Alkhuder Horia Mawlawi |
| author_sort | Lulwah Alkhuder |
| collection | DOAJ |
| description | Cushing syndrome is an endocrinological disorder characterized by increased free plasma glucocorticoids level. It is either due to an excessive endogenous release of steroids (e.g., pituitary adenoma or adrenal hyperplasia) or exogenous administration of steroids. In children, iatrogenic Cushing syndrome is the most common form of Cushing syndrome occurring in this age group. The vast majority of cases are due to oral or parenteral preparation of steroids, which are commonly prescribed for pulmonary, hematological, renal, or autoimmune pathologies. Topical preparations can rarely cause Cushing syndrome in young children, and only a few cases were reported in the literature, where the patients were older than 5 months of age. In this report, we present a three-month-old girl who developed iatrogenic Cushing syndrome due to prolonged and inappropriate use of topical clobetasol cream for napkin dermatitis. |
| format | Article |
| id | doaj-art-342b3c8b21b64cc59d33201e83ed06d5 |
| institution | OA Journals |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-342b3c8b21b64cc59d33201e83ed06d52025-08-20T02:24:17ZengWileyCase Reports in Pediatrics2090-68032090-68112019-01-01201910.1155/2019/26529612652961Infantile Iatrogenic Cushing Syndrome due to Topical SteroidsLulwah Alkhuder0Horia Mawlawi1Department of Pediatric Endocrinology, Prince Sultan Medical City, Riyadh, Saudi ArabiaDepartment of Pediatric Endocrinology, Prince Sultan Medical City, Riyadh, Saudi ArabiaCushing syndrome is an endocrinological disorder characterized by increased free plasma glucocorticoids level. It is either due to an excessive endogenous release of steroids (e.g., pituitary adenoma or adrenal hyperplasia) or exogenous administration of steroids. In children, iatrogenic Cushing syndrome is the most common form of Cushing syndrome occurring in this age group. The vast majority of cases are due to oral or parenteral preparation of steroids, which are commonly prescribed for pulmonary, hematological, renal, or autoimmune pathologies. Topical preparations can rarely cause Cushing syndrome in young children, and only a few cases were reported in the literature, where the patients were older than 5 months of age. In this report, we present a three-month-old girl who developed iatrogenic Cushing syndrome due to prolonged and inappropriate use of topical clobetasol cream for napkin dermatitis.http://dx.doi.org/10.1155/2019/2652961 |
| spellingShingle | Lulwah Alkhuder Horia Mawlawi Infantile Iatrogenic Cushing Syndrome due to Topical Steroids Case Reports in Pediatrics |
| title | Infantile Iatrogenic Cushing Syndrome due to Topical Steroids |
| title_full | Infantile Iatrogenic Cushing Syndrome due to Topical Steroids |
| title_fullStr | Infantile Iatrogenic Cushing Syndrome due to Topical Steroids |
| title_full_unstemmed | Infantile Iatrogenic Cushing Syndrome due to Topical Steroids |
| title_short | Infantile Iatrogenic Cushing Syndrome due to Topical Steroids |
| title_sort | infantile iatrogenic cushing syndrome due to topical steroids |
| url | http://dx.doi.org/10.1155/2019/2652961 |
| work_keys_str_mv | AT lulwahalkhuder infantileiatrogeniccushingsyndromeduetotopicalsteroids AT horiamawlawi infantileiatrogeniccushingsyndromeduetotopicalsteroids |