Longitudinal profile of plasma pregenomic RNA in patients with chronic hepatitis B infection on long-term nucleoside analogues and its interaction with clinical parameters

Longitudinal profile of plasma pregenomic RNA in patients with chronic hepatitis B infection on long-term nucleoside analogues and its interaction with clinical parameters

Background/Aims Plasma pregenomic hepatitis B virus RNA (pgRNA) is a novel biomarker in chronic hepatitis B infection (CHB). We aimed to describe the longitudinal profile of pgRNA and factors influencing its levels in CHB patients on nucleoside analogue (NUC). Methods Serial plasma samples from 1,35...

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Bibliographic Details
Main Authors: Lung-Yi Mak, Mark Anderson, Michael Stec, Matthew Shing-Hin Chung, Danny Ka-Ho Wong, Rex Wan-Hin Hui, Wai-Kay Seto, Gavin Cloherty, Man-Fung Yuen
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2025-04-01
Series:Clinical and Molecular Hepatology
Subjects:
hbv biomarkers
cirrhosis
aging
nucleoside analogue
Online Access:http://e-cmh.org/upload/pdf/cmh-2024-0724.pdf
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