Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes
Purpose. To compare the corneal biomechanical properties of keratoconic patients and age-matched controls using corneal visualization Scheimpflug technology (Corvis ST). Methods. Sixty keratoconic eyes from 47 keratoconus patients and 60 normal eyes from 60 controls were enrolled in this prospective...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/147516 |
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| author | Lei Tian Yi-Fei Huang Li-Qiang Wang Hua Bai Qun Wang Jing-Jing Jiang Ying Wu Min Gao |
| author_facet | Lei Tian Yi-Fei Huang Li-Qiang Wang Hua Bai Qun Wang Jing-Jing Jiang Ying Wu Min Gao |
| author_sort | Lei Tian |
| collection | DOAJ |
| description | Purpose. To compare the corneal biomechanical properties of keratoconic patients and age-matched controls using corneal visualization Scheimpflug technology (Corvis ST). Methods. Sixty keratoconic eyes from 47 keratoconus patients and 60 normal eyes from 60 controls were enrolled in this prospective study. Tomography and biomechanical parameters of all eyes were obtained with the Pentacam and Corvis ST, respectively. Intraocular pressure was measured using a Goldmann applanation tonometer.
Results. The tomography and biomechanical parameters of the keratoconic corneas were significantly different from those of the normal corneas except for the anterior chamber angle, first applanation length, the highest concavity time, and peak distance. The deformation amplitude was the best predictive parameter (area under the curve: 0.882), with a sensitivity of 81.7%, although there was a significant overlap between keratoconic and normal corneas that ranged from 1.0 to 1.4 mm. In both the keratoconus and control groups, the deformation amplitude was negatively correlated with intraocular pressure, central corneal thickness, and corneal volume at 3 and 5 mm. Conclusions. Corvis ST offers an alternative method for measuring corneal biomechanical properties. The possibility of classifying keratoconus based on deformation amplitude deserves clinical attention. |
| format | Article |
| id | doaj-art-3423049e257044c4a8f0e6ea5ae28e5b |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-3423049e257044c4a8f0e6ea5ae28e5b2025-02-03T00:59:13ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/147516147516Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal EyesLei Tian0Yi-Fei Huang1Li-Qiang Wang2Hua Bai3Qun Wang4Jing-Jing Jiang5Ying Wu6Min Gao7Department of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaDepartment of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaDepartment of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaDepartment of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaDepartment of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaDepartment of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaDepartment of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaDepartment of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, ChinaPurpose. To compare the corneal biomechanical properties of keratoconic patients and age-matched controls using corneal visualization Scheimpflug technology (Corvis ST). Methods. Sixty keratoconic eyes from 47 keratoconus patients and 60 normal eyes from 60 controls were enrolled in this prospective study. Tomography and biomechanical parameters of all eyes were obtained with the Pentacam and Corvis ST, respectively. Intraocular pressure was measured using a Goldmann applanation tonometer. Results. The tomography and biomechanical parameters of the keratoconic corneas were significantly different from those of the normal corneas except for the anterior chamber angle, first applanation length, the highest concavity time, and peak distance. The deformation amplitude was the best predictive parameter (area under the curve: 0.882), with a sensitivity of 81.7%, although there was a significant overlap between keratoconic and normal corneas that ranged from 1.0 to 1.4 mm. In both the keratoconus and control groups, the deformation amplitude was negatively correlated with intraocular pressure, central corneal thickness, and corneal volume at 3 and 5 mm. Conclusions. Corvis ST offers an alternative method for measuring corneal biomechanical properties. The possibility of classifying keratoconus based on deformation amplitude deserves clinical attention.http://dx.doi.org/10.1155/2014/147516 |
| spellingShingle | Lei Tian Yi-Fei Huang Li-Qiang Wang Hua Bai Qun Wang Jing-Jing Jiang Ying Wu Min Gao Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes Journal of Ophthalmology |
| title | Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes |
| title_full | Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes |
| title_fullStr | Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes |
| title_full_unstemmed | Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes |
| title_short | Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes |
| title_sort | corneal biomechanical assessment using corneal visualization scheimpflug technology in keratoconic and normal eyes |
| url | http://dx.doi.org/10.1155/2014/147516 |
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