Adenoid cystic carcinoma of the floor of the mouth – A rare presentation
Adenoid cystic carcinoma (ACC) is an unusual salivary gland malignancy that remains poorly understood. It is a slow growing but aggressive neoplasm with a tendency for recurrence. It is characterized by the proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid, and...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-11-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426815001153 |
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| author | Chandresh Jaiswara Neeraj Kumar Dhiman Akhilesh Kumar Singh Naresh Kumar Sharma Vishal Verma Arun Pandey |
| author_facet | Chandresh Jaiswara Neeraj Kumar Dhiman Akhilesh Kumar Singh Naresh Kumar Sharma Vishal Verma Arun Pandey |
| author_sort | Chandresh Jaiswara |
| collection | DOAJ |
| description | Adenoid cystic carcinoma (ACC) is an unusual salivary gland malignancy that remains poorly understood. It is a slow growing but aggressive neoplasm with a tendency for recurrence. It is characterized by the proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid, and cystic forms. Standard treatment, including surgery with postoperative radiation therapy, has attained reasonable local control rates, but distant metastases do not allow any improvement in the survival rate. The understanding of the molecular mechanisms driving ACC is quite rudimentary. We present a case of a 55-year-old female diagnosed with ACC involving the floor of the mouth with an aim to present the carcinoma's behavior, immunohistocytochemistry, the staining pattern, its treatment, and prognosis. |
| format | Article |
| id | doaj-art-3415fd6b03cd457f9eb8d9d11f7c04ac |
| institution | DOAJ |
| issn | 2212-4268 |
| language | English |
| publishDate | 2016-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-3415fd6b03cd457f9eb8d9d11f7c04ac2025-08-20T02:50:27ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682016-11-016S65S6910.1016/j.jobcr.2015.09.007Adenoid cystic carcinoma of the floor of the mouth – A rare presentationChandresh Jaiswara0Neeraj Kumar Dhiman1Akhilesh Kumar Singh2Naresh Kumar Sharma3Vishal Verma4Arun Pandey5Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., IndiaAssistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., IndiaService Senior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India; Corresponding author.Professor & Head, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., IndiaJunior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., IndiaJunior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., IndiaAdenoid cystic carcinoma (ACC) is an unusual salivary gland malignancy that remains poorly understood. It is a slow growing but aggressive neoplasm with a tendency for recurrence. It is characterized by the proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid, and cystic forms. Standard treatment, including surgery with postoperative radiation therapy, has attained reasonable local control rates, but distant metastases do not allow any improvement in the survival rate. The understanding of the molecular mechanisms driving ACC is quite rudimentary. We present a case of a 55-year-old female diagnosed with ACC involving the floor of the mouth with an aim to present the carcinoma's behavior, immunohistocytochemistry, the staining pattern, its treatment, and prognosis.http://www.sciencedirect.com/science/article/pii/S2212426815001153Adenoid cystic carcinomaMinor salivary glandFloor of the mouthMalignant |
| spellingShingle | Chandresh Jaiswara Neeraj Kumar Dhiman Akhilesh Kumar Singh Naresh Kumar Sharma Vishal Verma Arun Pandey Adenoid cystic carcinoma of the floor of the mouth – A rare presentation Journal of Oral Biology and Craniofacial Research Adenoid cystic carcinoma Minor salivary gland Floor of the mouth Malignant |
| title | Adenoid cystic carcinoma of the floor of the mouth – A rare presentation |
| title_full | Adenoid cystic carcinoma of the floor of the mouth – A rare presentation |
| title_fullStr | Adenoid cystic carcinoma of the floor of the mouth – A rare presentation |
| title_full_unstemmed | Adenoid cystic carcinoma of the floor of the mouth – A rare presentation |
| title_short | Adenoid cystic carcinoma of the floor of the mouth – A rare presentation |
| title_sort | adenoid cystic carcinoma of the floor of the mouth a rare presentation |
| topic | Adenoid cystic carcinoma Minor salivary gland Floor of the mouth Malignant |
| url | http://www.sciencedirect.com/science/article/pii/S2212426815001153 |
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