Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia

A 23-year-old woman with a history of surgically repaired pulmonary atresia and subsequent severe tricuspid, pulmonic regurgitation, and obesity class II (body mass index, 37.5 kg/m2) presented with 4 months of unexplained hypoxemia and dyspnea that began after an uncomplicated laparoscopic cholecys...

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Main Authors: Emily Strickland, Zachary Kerosky, Joseph Krivda, Takor Arrey-Mbi
Format: Article
Language:English
Published: American College of Physicians 2023-02-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.1124
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author Emily Strickland
Zachary Kerosky
Joseph Krivda
Takor Arrey-Mbi
author_facet Emily Strickland
Zachary Kerosky
Joseph Krivda
Takor Arrey-Mbi
author_sort Emily Strickland
collection DOAJ
description A 23-year-old woman with a history of surgically repaired pulmonary atresia and subsequent severe tricuspid, pulmonic regurgitation, and obesity class II (body mass index, 37.5 kg/m2) presented with 4 months of unexplained hypoxemia and dyspnea that began after an uncomplicated laparoscopic cholecystectomy. Further evaluation found hypoxia in the upright position that promptly resolved in the supine position consistent with platypnea-orthodeoxia syndrome. She was found to have a patent foramen ovale that was percutaneously closed with resolution of symptoms. Platypnea-orthodeoxia syndrome incited by laparoscopic abdominal surgery has been rarely reported in literature, but should be considered in the differential of postoperative dyspnea.
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publisher American College of Physicians
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series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-341439cc7b8845729b9a67e8da29ff202025-08-20T02:17:33ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642023-02-012210.7326/aimcc.2022.1124Platypnea-Orthodeoxia Syndrome: A Rare Cause of HypoxiaEmily Strickland0Zachary Kerosky1Joseph Krivda2Takor Arrey-Mbi31Department of Medicine, Madigan Army Medical Center, Tacoma, Washington1Department of Medicine, Madigan Army Medical Center, Tacoma, Washington2F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland3Cardiology Department, Madigan Army Medical Center, Tacoma, WashingtonA 23-year-old woman with a history of surgically repaired pulmonary atresia and subsequent severe tricuspid, pulmonic regurgitation, and obesity class II (body mass index, 37.5 kg/m2) presented with 4 months of unexplained hypoxemia and dyspnea that began after an uncomplicated laparoscopic cholecystectomy. Further evaluation found hypoxia in the upright position that promptly resolved in the supine position consistent with platypnea-orthodeoxia syndrome. She was found to have a patent foramen ovale that was percutaneously closed with resolution of symptoms. Platypnea-orthodeoxia syndrome incited by laparoscopic abdominal surgery has been rarely reported in literature, but should be considered in the differential of postoperative dyspnea.https://www.acpjournals.org/doi/10.7326/aimcc.2022.1124
spellingShingle Emily Strickland
Zachary Kerosky
Joseph Krivda
Takor Arrey-Mbi
Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia
Annals of Internal Medicine: Clinical Cases
title Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia
title_full Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia
title_fullStr Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia
title_full_unstemmed Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia
title_short Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia
title_sort platypnea orthodeoxia syndrome a rare cause of hypoxia
url https://www.acpjournals.org/doi/10.7326/aimcc.2022.1124
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AT zacharykerosky platypneaorthodeoxiasyndromeararecauseofhypoxia
AT josephkrivda platypneaorthodeoxiasyndromeararecauseofhypoxia
AT takorarreymbi platypneaorthodeoxiasyndromeararecauseofhypoxia