Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia

A 23-year-old woman with a history of surgically repaired pulmonary atresia and subsequent severe tricuspid, pulmonic regurgitation, and obesity class II (body mass index, 37.5 kg/m2) presented with 4 months of unexplained hypoxemia and dyspnea that began after an uncomplicated laparoscopic cholecys...

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Bibliographic Details
Main Authors: Emily Strickland, Zachary Kerosky, Joseph Krivda, Takor Arrey-Mbi
Format: Article
Language:English
Published: American College of Physicians 2023-02-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.1124
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Summary:A 23-year-old woman with a history of surgically repaired pulmonary atresia and subsequent severe tricuspid, pulmonic regurgitation, and obesity class II (body mass index, 37.5 kg/m2) presented with 4 months of unexplained hypoxemia and dyspnea that began after an uncomplicated laparoscopic cholecystectomy. Further evaluation found hypoxia in the upright position that promptly resolved in the supine position consistent with platypnea-orthodeoxia syndrome. She was found to have a patent foramen ovale that was percutaneously closed with resolution of symptoms. Platypnea-orthodeoxia syndrome incited by laparoscopic abdominal surgery has been rarely reported in literature, but should be considered in the differential of postoperative dyspnea.
ISSN:2767-7664