microRNA-183–5p induces cell density-dependent apoptosis through the regulation of Presenilin 2

microRNA-183–5p induces cell density-dependent apoptosis through the regulation of Presenilin 2

Cells undergo apoptosis under dense culture condition to maintain homeostasis. Impaired apoptosis may contribute to the excessive accumulation of pathogenetic cells in such diseases as cancer and organ fibrosis. Elucidating the molecular mechanisms regulating cell density-dependent apoptosis may pro...

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Bibliographic Details
Main Authors: Yuki Yabuuchi, Yosuke Matsuno, Kai Yazaki, Wei Zhen Ting, Kengo Nishino, Sosuke Matsumura, Kenya Kuramoto, Kazufumi Yoshida, Masashi Matsuyama, Takumi Kiwamoto, Yuko Morishima, Nobuyuki Hizawa
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:European Journal of Cell Biology
Subjects:
Akt
B cell lymphoma-2
Notch signaling pathway
microRNA 183–5p
Phosphatidylinositol-3 kinase
Presenilin 2
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933525000196
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