Primary Intraosseous Synovial Sarcoma in the Mandible
Synovial sarcoma (SS) is a rare malignant mesenchymal tumor that mainly occurs in body extremities, being uncommon in the head and neck region. In the present study, we described a case of primary intraosseous SS arising in the mandible of a 22-year-old young male. The patient reported a painful swe...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/9945591 |
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| author | Lucas Novaes Teixeira Eduardo Zambaldi da Cruz Ana Cláudia Garcia Rosa Anderson Abdo Rodrigues Fabrício Passador-Santos Vera Cavalcanti de Araújo Andresa Borges Soares |
| author_facet | Lucas Novaes Teixeira Eduardo Zambaldi da Cruz Ana Cláudia Garcia Rosa Anderson Abdo Rodrigues Fabrício Passador-Santos Vera Cavalcanti de Araújo Andresa Borges Soares |
| author_sort | Lucas Novaes Teixeira |
| collection | DOAJ |
| description | Synovial sarcoma (SS) is a rare malignant mesenchymal tumor that mainly occurs in body extremities, being uncommon in the head and neck region. In the present study, we described a case of primary intraosseous SS arising in the mandible of a 22-year-old young male. The patient reported a painful swelling on the left side of the mandible for the last 7 months. Imaging exams showed the presence of an expansive and multilocular radiolucent lesion, extending from the left condyle to the mandibular body. The clinic diagnostic hypotheses were ameloblastoma or malignant neoplasm. Histologically, the lesion was characterized by a proliferation of spindle cells exhibiting vesicular nuclei and evident nucleolus. Neoplastic cells were positive for AE1/AE3, cytokeratin 7, vimentin, CD-99, and TLE-1 and negative for CD-34, S-100, SMA, and HHF-35. A combination of clinical, histologic, and immunohistochemical characteristics supported the diagnosis of SS. The patient was referred for treatment, and preoperative exams did not reveal any other tumor foci in the body of the patient. The final diagnosis was of a primary intraosseous SS of the mandible. |
| format | Article |
| id | doaj-art-340688dceeb04d94a1ab443d977bccfe |
| institution | Kabale University |
| issn | 2090-6714 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-340688dceeb04d94a1ab443d977bccfe2025-02-03T06:00:00ZengWileyCase Reports in Oncological Medicine2090-67142021-01-01202110.1155/2021/9945591Primary Intraosseous Synovial Sarcoma in the MandibleLucas Novaes Teixeira0Eduardo Zambaldi da Cruz1Ana Cláudia Garcia Rosa2Anderson Abdo Rodrigues3Fabrício Passador-Santos4Vera Cavalcanti de Araújo5Andresa Borges Soares6Faculdade São Leopoldo MandicFaculdade São Leopoldo MandicFaculdade São Leopoldo MandicSchool of MedicineFaculdade São Leopoldo MandicFaculdade São Leopoldo MandicFaculdade São Leopoldo MandicSynovial sarcoma (SS) is a rare malignant mesenchymal tumor that mainly occurs in body extremities, being uncommon in the head and neck region. In the present study, we described a case of primary intraosseous SS arising in the mandible of a 22-year-old young male. The patient reported a painful swelling on the left side of the mandible for the last 7 months. Imaging exams showed the presence of an expansive and multilocular radiolucent lesion, extending from the left condyle to the mandibular body. The clinic diagnostic hypotheses were ameloblastoma or malignant neoplasm. Histologically, the lesion was characterized by a proliferation of spindle cells exhibiting vesicular nuclei and evident nucleolus. Neoplastic cells were positive for AE1/AE3, cytokeratin 7, vimentin, CD-99, and TLE-1 and negative for CD-34, S-100, SMA, and HHF-35. A combination of clinical, histologic, and immunohistochemical characteristics supported the diagnosis of SS. The patient was referred for treatment, and preoperative exams did not reveal any other tumor foci in the body of the patient. The final diagnosis was of a primary intraosseous SS of the mandible.http://dx.doi.org/10.1155/2021/9945591 |
| spellingShingle | Lucas Novaes Teixeira Eduardo Zambaldi da Cruz Ana Cláudia Garcia Rosa Anderson Abdo Rodrigues Fabrício Passador-Santos Vera Cavalcanti de Araújo Andresa Borges Soares Primary Intraosseous Synovial Sarcoma in the Mandible Case Reports in Oncological Medicine |
| title | Primary Intraosseous Synovial Sarcoma in the Mandible |
| title_full | Primary Intraosseous Synovial Sarcoma in the Mandible |
| title_fullStr | Primary Intraosseous Synovial Sarcoma in the Mandible |
| title_full_unstemmed | Primary Intraosseous Synovial Sarcoma in the Mandible |
| title_short | Primary Intraosseous Synovial Sarcoma in the Mandible |
| title_sort | primary intraosseous synovial sarcoma in the mandible |
| url | http://dx.doi.org/10.1155/2021/9945591 |
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