Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bones
Objective: To compare and analyze the image features of X-ray, computerized tomography (CT), and magnetic resonance imaging (MRI) in patients with chondroblastoma (CB) in tubular and non-tubular bones, to improve the preoperative diagnostic accuracy and follow-up the postoperative recurrence rate. M...
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Elsevier
2025-06-01
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| Series: | Journal of Bone Oncology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137425000326 |
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| author | Xiang Feng Yuxiang Fang Hanhua Yu Zhanqiang Song Xiangrong Guo Man Yang |
| author_facet | Xiang Feng Yuxiang Fang Hanhua Yu Zhanqiang Song Xiangrong Guo Man Yang |
| author_sort | Xiang Feng |
| collection | DOAJ |
| description | Objective: To compare and analyze the image features of X-ray, computerized tomography (CT), and magnetic resonance imaging (MRI) in patients with chondroblastoma (CB) in tubular and non-tubular bones, to improve the preoperative diagnostic accuracy and follow-up the postoperative recurrence rate. Methods: Sixty-one CB patients confirmed by surgical pathology in our hospital and Huazhong University of Science and Technology Tongji Medical College Affiliated Union Hospital from August 2013 to March 2024 were included in this study. Their clinical, image, and pathological data were retrospectively collected and analyzed. Clinical data included age and gender. Image data included lesion size, lobulation, distensibility, bone crest, calcification, sclerotic margin, periosteal reaction, soft tissue swelling, fluid level, and aneurysmal bone cyst (ABC). Pathologic data included pathological findings and immunohistochemistry (IHC).ResultsThe average onset age in tubular bone and non-tubular bone groups was 17.3 ± 5.5 and 25.6 ± 5.7 respectively (p = 0.00). The percentage of distensibility with or without was 37 %, 63 %, 69 % and 31 % (p = 0.01), the percentage of bone crest with or without was 46 %, 54 %, 77 % and 20 % (p = 0.01), and the percentage of fluid level with or without was 17 %, 83 %, 62 % and 38 % in tubular bone and non-tubular bone groups, respectively (p = 0.00). CB was predominantly non-calcified or mottled calcification in patients with lesions less than 12 months and patchy or cloudy calcification in patients with lesions more than 12 months. CB of the calcaneus and talus accounted for 54 % of the CB of the non-tubular bones. There was one case of preoperative malignant lesion and one case of postoperative recurrence. Conclusion: Lesions in CB patients in non-tubular bone are swollen and are prone to form a coarse bone creast and fluid level, and the bone swells even more obviously when CB is combined with ABC. There is a low possibility of malignant transformation and postoperative recurrence in CB patients. |
| format | Article |
| id | doaj-art-34039d2992a949928c1e228fcf45fefc |
| institution | DOAJ |
| issn | 2212-1374 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Bone Oncology |
| spelling | doaj-art-34039d2992a949928c1e228fcf45fefc2025-08-20T03:20:33ZengElsevierJournal of Bone Oncology2212-13742025-06-015210069110.1016/j.jbo.2025.100691Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bonesXiang Feng0Yuxiang Fang1Hanhua Yu2Zhanqiang Song3Xiangrong Guo4Man Yang5Department of Radiology, Wuhan Fourth Hospital, Wuhan City, Hubei Province 430000 ChinaDepartment of Radiology, Huazhong University of Science and Technology Tongji Medical College Affiliated Union Hospital, Wuhan City, Hubei Province 430000 ChinaDepartment of Radiology, Wuhan Fourth Hospital, Wuhan City, Hubei Province 430000 ChinaDepartment of Radiology, Wuhan Fourth Hospital, Wuhan City, Hubei Province 430000 ChinaDepartment of Radiology, Wuhan Fourth Hospital, Wuhan City, Hubei Province 430000 ChinaDepartment of Radiology, Wuhan Fourth Hospital, Wuhan City, Hubei Province 430000 China; Corresponding author at: Department of Radiology, Wuhan Fourth Hospital, 473 Hanzheng Street, Qiaokou District, Wuhan City, Hubei Province 430000, China.Objective: To compare and analyze the image features of X-ray, computerized tomography (CT), and magnetic resonance imaging (MRI) in patients with chondroblastoma (CB) in tubular and non-tubular bones, to improve the preoperative diagnostic accuracy and follow-up the postoperative recurrence rate. Methods: Sixty-one CB patients confirmed by surgical pathology in our hospital and Huazhong University of Science and Technology Tongji Medical College Affiliated Union Hospital from August 2013 to March 2024 were included in this study. Their clinical, image, and pathological data were retrospectively collected and analyzed. Clinical data included age and gender. Image data included lesion size, lobulation, distensibility, bone crest, calcification, sclerotic margin, periosteal reaction, soft tissue swelling, fluid level, and aneurysmal bone cyst (ABC). Pathologic data included pathological findings and immunohistochemistry (IHC).ResultsThe average onset age in tubular bone and non-tubular bone groups was 17.3 ± 5.5 and 25.6 ± 5.7 respectively (p = 0.00). The percentage of distensibility with or without was 37 %, 63 %, 69 % and 31 % (p = 0.01), the percentage of bone crest with or without was 46 %, 54 %, 77 % and 20 % (p = 0.01), and the percentage of fluid level with or without was 17 %, 83 %, 62 % and 38 % in tubular bone and non-tubular bone groups, respectively (p = 0.00). CB was predominantly non-calcified or mottled calcification in patients with lesions less than 12 months and patchy or cloudy calcification in patients with lesions more than 12 months. CB of the calcaneus and talus accounted for 54 % of the CB of the non-tubular bones. There was one case of preoperative malignant lesion and one case of postoperative recurrence. Conclusion: Lesions in CB patients in non-tubular bone are swollen and are prone to form a coarse bone creast and fluid level, and the bone swells even more obviously when CB is combined with ABC. There is a low possibility of malignant transformation and postoperative recurrence in CB patients.http://www.sciencedirect.com/science/article/pii/S2212137425000326ChondroblastomaTubular boneNon-tubular boneX-rayCTMRI |
| spellingShingle | Xiang Feng Yuxiang Fang Hanhua Yu Zhanqiang Song Xiangrong Guo Man Yang Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bones Journal of Bone Oncology Chondroblastoma Tubular bone Non-tubular bone X-ray CT MRI |
| title | Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bones |
| title_full | Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bones |
| title_fullStr | Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bones |
| title_full_unstemmed | Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bones |
| title_short | Comparative analysis of X-ray, CT, and MRI images in patients with chondroblastoma in tubular and non-tubular bones |
| title_sort | comparative analysis of x ray ct and mri images in patients with chondroblastoma in tubular and non tubular bones |
| topic | Chondroblastoma Tubular bone Non-tubular bone X-ray CT MRI |
| url | http://www.sciencedirect.com/science/article/pii/S2212137425000326 |
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