Risk factors for cholelithiasis (literature review)

Relevance. Cholelithiasis is a multifactorial disease, which is characterized by the formation of concretions in the gallbladder. Currently, cholelithiasis is one of the most common diseases in the practice of a general practitioner, gastroenterologist, surgeon. The study and identification among th...

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Main Authors: B. A. Sakhabetdinov, A. I. Kurbangaleev, E. A. Khizbullina, R. R. Shaydullina, A. S. Bobrikhina, D. R. Sayapova
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2025-06-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
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Online Access:https://vestnik.reaviz.ru/jour/article/view/1201
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author B. A. Sakhabetdinov
A. I. Kurbangaleev
E. A. Khizbullina
R. R. Shaydullina
A. S. Bobrikhina
D. R. Sayapova
author_facet B. A. Sakhabetdinov
A. I. Kurbangaleev
E. A. Khizbullina
R. R. Shaydullina
A. S. Bobrikhina
D. R. Sayapova
author_sort B. A. Sakhabetdinov
collection DOAJ
description Relevance. Cholelithiasis is a multifactorial disease, which is characterized by the formation of concretions in the gallbladder. Currently, cholelithiasis is one of the most common diseases in the practice of a general practitioner, gastroenterologist, surgeon. The study and identification among the population of the factors of development of this pathology contributes to earlier diagnosis, treatment of gallstone disease, prevention.The aim of the study is to improve the results of diagnostics and treatment of patients with GI by revealing the risk factors of development and allocation of risk groups for this pathology. Materials and methods: review of modern foreign and domestic literature on modifiable and non-modifiable risk factors of cholelithiasis, their participation in pathogenesis.Results. Among modifiable development factors the most important for the development of cholelithiasis the following should be emphasized: excessive body weight, forced weight loss, low physical activity, bad habits, hormone therapy.Conclusions. The most significant risk factors for the development of cholelithiasis have been identified. Special attention was paid to the consideration of hypodynamia, obesity, bad habits, drugs, neuroendocrine dysfunction on the probability of GI. An association between various diseases (type 2 diabetes mellitus, hypothyroidism, nonalcoholic fatty liver disease, Crohn's disease) and the presence of concrements in the gallbladder has been found. It is established that various risk factors can influence on pathogenesis of cholelithiasis that is reflected on clinical picture of the disease depending on their specificity and influence on the organism.
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institution Kabale University
issn 2226-762X
2782-1579
language Russian
publishDate 2025-06-01
publisher Private institution educational organization of higher education "Medical University "ReaViz"
record_format Article
series Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
spelling doaj-art-340230e0c191404089f5d1a0f9b0efa22025-08-20T03:59:21ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792025-06-011529710410.20340/vmi-rvz.2025.2.CLIN.5728Risk factors for cholelithiasis (literature review)B. A. Sakhabetdinov0A. I. Kurbangaleev1E. A. Khizbullina2R. R. Shaydullina3A. S. Bobrikhina4D. R. Sayapova5Kazan State Medical UniversityKazan State Medical UniversityAlmazov National Medical Research CenterKazan State Medical UniversityKazan State Medical UniversityKazan State Medical UniversityRelevance. Cholelithiasis is a multifactorial disease, which is characterized by the formation of concretions in the gallbladder. Currently, cholelithiasis is one of the most common diseases in the practice of a general practitioner, gastroenterologist, surgeon. The study and identification among the population of the factors of development of this pathology contributes to earlier diagnosis, treatment of gallstone disease, prevention.The aim of the study is to improve the results of diagnostics and treatment of patients with GI by revealing the risk factors of development and allocation of risk groups for this pathology. Materials and methods: review of modern foreign and domestic literature on modifiable and non-modifiable risk factors of cholelithiasis, their participation in pathogenesis.Results. Among modifiable development factors the most important for the development of cholelithiasis the following should be emphasized: excessive body weight, forced weight loss, low physical activity, bad habits, hormone therapy.Conclusions. The most significant risk factors for the development of cholelithiasis have been identified. Special attention was paid to the consideration of hypodynamia, obesity, bad habits, drugs, neuroendocrine dysfunction on the probability of GI. An association between various diseases (type 2 diabetes mellitus, hypothyroidism, nonalcoholic fatty liver disease, Crohn's disease) and the presence of concrements in the gallbladder has been found. It is established that various risk factors can influence on pathogenesis of cholelithiasis that is reflected on clinical picture of the disease depending on their specificity and influence on the organism.https://vestnik.reaviz.ru/jour/article/view/1201cholelithiasis [d002769]risk factors [d012307]cholesterol stones [d015892]gallbladder [d005704]cholecystitis [d002764]obesity [d009765]metabolic syndrome [d024821]dyslipidemia [d050171]hypercholesterolemia [d006937]epidemiology of gallstone disease [d002769]
spellingShingle B. A. Sakhabetdinov
A. I. Kurbangaleev
E. A. Khizbullina
R. R. Shaydullina
A. S. Bobrikhina
D. R. Sayapova
Risk factors for cholelithiasis (literature review)
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
cholelithiasis [d002769]
risk factors [d012307]
cholesterol stones [d015892]
gallbladder [d005704]
cholecystitis [d002764]
obesity [d009765]
metabolic syndrome [d024821]
dyslipidemia [d050171]
hypercholesterolemia [d006937]
epidemiology of gallstone disease [d002769]
title Risk factors for cholelithiasis (literature review)
title_full Risk factors for cholelithiasis (literature review)
title_fullStr Risk factors for cholelithiasis (literature review)
title_full_unstemmed Risk factors for cholelithiasis (literature review)
title_short Risk factors for cholelithiasis (literature review)
title_sort risk factors for cholelithiasis literature review
topic cholelithiasis [d002769]
risk factors [d012307]
cholesterol stones [d015892]
gallbladder [d005704]
cholecystitis [d002764]
obesity [d009765]
metabolic syndrome [d024821]
dyslipidemia [d050171]
hypercholesterolemia [d006937]
epidemiology of gallstone disease [d002769]
url https://vestnik.reaviz.ru/jour/article/view/1201
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AT rrshaydullina riskfactorsforcholelithiasisliteraturereview
AT asbobrikhina riskfactorsforcholelithiasisliteraturereview
AT drsayapova riskfactorsforcholelithiasisliteraturereview