Deciphering the prognostic impact of aberrant DNA methylation on ANGPT1 gene in breast cancer

Deciphering the prognostic impact of aberrant DNA methylation on ANGPT1 gene in breast cancer

Abstract Breast cancer (BC) is a multifaceted disease distinguished by a range of molecular subtypes and varying clinical prognoses. The involvement of DNA methylation in the dysregulation of gene expression has been linked to the development and progression of BC. Therefore, this study aimed to inv...

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Bibliographic Details
Main Authors: Mansour Alsaleem, Samar Sindi, Safiah Alhazmi, Sabah Hassan, Magdah Ganash, Najla Alburae, Shadi Alkhayyat, Ayman Linjawi, Aisha Elaimi, Saif A. Alharthy, Khloud Algothmi, Reem Farsi, Ghadeer Alrefaei, Nouf Alsubhi, Norah Hamdi, Heba Alkhatabi
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Breast cancer
DNA methylation
Biomarker
ANGPT1
5-aza-2'-deoxycytidine
Online Access:https://doi.org/10.1038/s41598-025-90001-7
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