Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia

Acute Limb Ischemia (ALI) is a sudden decrease in limb perfusion with a potential of limb loss and is an indication for immediate vascular intervention. Apart from reducing the quality of life, the mortality rate in ALI is reported to be high, i.e., around 40%. Neutrophil Lymphocyte Ratio (NLR) can...

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Main Authors: Putie Hapsari, Teguh Marfen Djajakusumah, Hendri Bayu Nugroho
Format: Article
Language:English
Published: Universitas Padjajaran 2025-03-01
Series:Majalah Kedokteran Bandung
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Online Access:https://journal.fk.unpad.ac.id/index.php/mkb/article/view/3848
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author Putie Hapsari
Teguh Marfen Djajakusumah
Hendri Bayu Nugroho
author_facet Putie Hapsari
Teguh Marfen Djajakusumah
Hendri Bayu Nugroho
author_sort Putie Hapsari
collection DOAJ
description Acute Limb Ischemia (ALI) is a sudden decrease in limb perfusion with a potential of limb loss and is an indication for immediate vascular intervention. Apart from reducing the quality of life, the mortality rate in ALI is reported to be high, i.e., around 40%. Neutrophil Lymphocyte Ratio (NLR) can be used to reflect the inflammatory process in this condition. This study aimed to assess the correlation of NLR to mortality rate in ALI Rutherford Category III patients treated in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. This was a cross-sectional analytical observative retrospective study on data collected from medical records of ALI Rutherford Category III patients treated in the hospital from 2019 to 2022. Sampling was performed consecutively and data were processed using the SPSS with univariate analysis and bivariate analysis using Kendall's tau b analysis test. Results demonstrated that of a total of 46 patients, the majority were female patients (n=31) and 28 patients died. The mean NLR levels in patients who survived was 5.8, in contrast with 9.7 observed among those who died. The statistical test results showed a significant correlation between the NLR and mortality rate of ALI Rutherford category III patients (p
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series Majalah Kedokteran Bandung
spelling doaj-art-33fa50672a1b40fdb8048ffb79444d7b2025-08-20T03:58:14ZengUniversitas PadjajaranMajalah Kedokteran Bandung0126-074X2338-62232025-03-01571626810.15395/mkb.v57.38481831Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb IschemiaPutie Hapsari0Teguh Marfen Djajakusumah1Hendri Bayu Nugroho2Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, BandungDivision of Vascular Surgery, Department of Surgery, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, BandungDepartment of Surgery, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, BandungAcute Limb Ischemia (ALI) is a sudden decrease in limb perfusion with a potential of limb loss and is an indication for immediate vascular intervention. Apart from reducing the quality of life, the mortality rate in ALI is reported to be high, i.e., around 40%. Neutrophil Lymphocyte Ratio (NLR) can be used to reflect the inflammatory process in this condition. This study aimed to assess the correlation of NLR to mortality rate in ALI Rutherford Category III patients treated in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. This was a cross-sectional analytical observative retrospective study on data collected from medical records of ALI Rutherford Category III patients treated in the hospital from 2019 to 2022. Sampling was performed consecutively and data were processed using the SPSS with univariate analysis and bivariate analysis using Kendall's tau b analysis test. Results demonstrated that of a total of 46 patients, the majority were female patients (n=31) and 28 patients died. The mean NLR levels in patients who survived was 5.8, in contrast with 9.7 observed among those who died. The statistical test results showed a significant correlation between the NLR and mortality rate of ALI Rutherford category III patients (phttps://journal.fk.unpad.ac.id/index.php/mkb/article/view/3848acute limb ischemia (ali), nlr, mortality rate
spellingShingle Putie Hapsari
Teguh Marfen Djajakusumah
Hendri Bayu Nugroho
Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia
Majalah Kedokteran Bandung
acute limb ischemia (ali), nlr, mortality rate
title Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia
title_full Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia
title_fullStr Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia
title_full_unstemmed Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia
title_short Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia
title_sort neutrophil lymphocyte ratio and mortality in patients with acute limb ischemia
topic acute limb ischemia (ali), nlr, mortality rate
url https://journal.fk.unpad.ac.id/index.php/mkb/article/view/3848
work_keys_str_mv AT putiehapsari neutrophillymphocyteratioandmortalityinpatientswithacutelimbischemia
AT teguhmarfendjajakusumah neutrophillymphocyteratioandmortalityinpatientswithacutelimbischemia
AT hendribayunugroho neutrophillymphocyteratioandmortalityinpatientswithacutelimbischemia