Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series Analysis

Introduction: Herbal medications have been utilized for centuries to treat various ailments, yet their potential to induce renal damage is often underestimated. The popularity of herbal remedies, especially in rural India, stems from cultural beliefs in their holistic healing properties....

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Main Authors: Ashok Bhat, Rohan Desai, Mahesha Vankalakunti
Format: Article
Language:English
Published: Karger Publishers 2025-03-01
Series:Case Reports in Nephrology and Dialysis
Online Access:https://karger.com/article/doi/10.1159/000545186
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author Ashok Bhat
Rohan Desai
Mahesha Vankalakunti
author_facet Ashok Bhat
Rohan Desai
Mahesha Vankalakunti
author_sort Ashok Bhat
collection DOAJ
description Introduction: Herbal medications have been utilized for centuries to treat various ailments, yet their potential to induce renal damage is often underestimated. The popularity of herbal remedies, especially in rural India, stems from cultural beliefs in their holistic healing properties. Case Presentations: This case series comprises 4 patients exhibiting varied renal presentations linked to herbal medication usage. Notably, oxalate nephropathy emerged as a predominant finding. Through comprehensive clinical assessments and renal biopsies, we elucidated the pathophysiological mechanisms underlying herbal nephrotoxicity. Timely recognition and discontinuation of the offending herb, alongside tailored therapeutic interventions like corticosteroid administration, facilitated favourable patient outcomes. Conclusion: These cases underscore the importance of considering herbal remedies as potential culprits in renal dysfunction, particularly in regions where their usage is prevalent. Our findings emphasize the imperative for healthcare practitioners to proactively inquire about herbal medication use in patients with renal failure. Heightened awareness and further research into the safety and mechanisms of herbal nephrotoxicity are essential for optimizing patient care and preventing herb-induced kidney injury.
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series Case Reports in Nephrology and Dialysis
spelling doaj-art-33f792cc45e142b7a2afb2514f7b59712025-08-20T01:51:04ZengKarger PublishersCase Reports in Nephrology and Dialysis2296-97052025-03-01151606910.1159/000545186Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series AnalysisAshok BhatRohan DesaiMahesha Vankalakunti Introduction: Herbal medications have been utilized for centuries to treat various ailments, yet their potential to induce renal damage is often underestimated. The popularity of herbal remedies, especially in rural India, stems from cultural beliefs in their holistic healing properties. Case Presentations: This case series comprises 4 patients exhibiting varied renal presentations linked to herbal medication usage. Notably, oxalate nephropathy emerged as a predominant finding. Through comprehensive clinical assessments and renal biopsies, we elucidated the pathophysiological mechanisms underlying herbal nephrotoxicity. Timely recognition and discontinuation of the offending herb, alongside tailored therapeutic interventions like corticosteroid administration, facilitated favourable patient outcomes. Conclusion: These cases underscore the importance of considering herbal remedies as potential culprits in renal dysfunction, particularly in regions where their usage is prevalent. Our findings emphasize the imperative for healthcare practitioners to proactively inquire about herbal medication use in patients with renal failure. Heightened awareness and further research into the safety and mechanisms of herbal nephrotoxicity are essential for optimizing patient care and preventing herb-induced kidney injury. https://karger.com/article/doi/10.1159/000545186
spellingShingle Ashok Bhat
Rohan Desai
Mahesha Vankalakunti
Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series Analysis
Case Reports in Nephrology and Dialysis
title Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series Analysis
title_full Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series Analysis
title_fullStr Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series Analysis
title_full_unstemmed Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series Analysis
title_short Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage – A Case Series Analysis
title_sort unveiling the hidden risks herbal medicine induced renal damage a case series analysis
url https://karger.com/article/doi/10.1159/000545186
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