IGF-1R Inhibition Suppresses Cell Proliferation and Increases Radiosensitivity in Nasopharyngeal Carcinoma Cells
Although ionizing radiation (IR) has provided considerable improvements in nasopharyngeal carcinoma (NPC) treatment, radioresistance is still a major threat for some subsets of patients. The insulin-like growth factor-1 receptor (IGF-1R) signaling pathway is tightly regulated and plays critical role...
Saved in:
Main Authors: | Zhe Wang, Guangyan Liu, Jiwei Mao, Min Xie, Ming Zhao, Xuefen Guo, Shanshan Liang, Heming Li, Xuefeng Li, Ruoyu Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2019/5497467 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma
by: Jie Chen, et al.
Published: (2025-02-01) -
Identification and validation of a prognostic risk model based on radiosensitivity-related genes in nasopharyngeal carcinoma
by: Yi Li, et al.
Published: (2025-02-01) -
Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types
by: Leif R. Neitzel, et al.
Published: (2025-02-01) -
LAMB1 promotes proliferation and metastasis in nasopharyngeal carcinoma and shapes the immune-suppressive tumor microenvironment
by: Enzi Feng, et al.
Published: (2025-03-01) -
Exosomal miR-543 Inhibits the Proliferation of Ovarian Cancer by Targeting IGF2
by: Shupei Zhang, et al.
Published: (2022-01-01)