Upregulation of Scavenger Receptor BI by Hepatic Nuclear Factor 4α through a Peroxisome Proliferator-Activated Receptor γ-Dependent Mechanism in Liver

Upregulation of Scavenger Receptor BI by Hepatic Nuclear Factor 4α through a Peroxisome Proliferator-Activated Receptor γ-Dependent Mechanism in Liver

Hepatic nuclear factor 4α (HNF4α) modulates the transcriptional activation of numerous metabolic genes in liver. In this study, gene-array analysis revealed that HNF4α overexpression increased peroxisome proliferator-activated receptorγ (PPARγ) greatly in cultured rat primary hepatocytes. PPAR-respo...

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Bibliographic Details
Main Authors: Yi Zhang, Chen Shen, Ding Ai, Xuefen Xie, Yi Zhu
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2011/164925
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