Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children
The purpose of the study was to determine the risk factors affecting the development of asthma combined with gastroesophageal reflux disease (GERD). Seventy children aged 5-17 years with asthma were examined. They were divided to two groups: group 1 (50 children with asthma and GERD), and group 2 (2...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2020-12-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/221399 |
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| author | T.R. Umanets A.A. Buratynska S.I. Tolkach L.S. Stepanova S.Yu. Matveeva T.V. Kondratenkova O.A. Smirnova T.A. Garaschenko V.F. Lapshyn Yu.G. Antipkin |
| author_facet | T.R. Umanets A.A. Buratynska S.I. Tolkach L.S. Stepanova S.Yu. Matveeva T.V. Kondratenkova O.A. Smirnova T.A. Garaschenko V.F. Lapshyn Yu.G. Antipkin |
| author_sort | T.R. Umanets |
| collection | DOAJ |
| description | The purpose of the study was to determine the risk factors affecting the development of asthma combined with gastroesophageal reflux disease (GERD). Seventy children aged 5-17 years with asthma were examined. They were divided to two groups: group 1 (50 children with asthma and GERD), and group 2 (20 children with isolated asthma). Medical history data were collected through specially designed questionnaire for parents. It was determined that the perinatal risk factors that likely contributed to developing co-morbid asthma and GERD were a threatened miscarriage (OR=6.65; 95% CI, 1.7-25.6, p=0.003), acute respiratory illnesses during pregnancy (OR=6.52; 95% CI, 1.4-31.2, p=0.008), polyhydramnios (p=0.039) and uterine inertia (p=0.0003). Food hypersensitivity in the first year of life, the severity of asthma in examined children played role in increasing the risk of developing asthma combined with GERD (OR=4.83; 95% CI, 1.3-18.6, p=0.013 and OR=4.45; 95% CI, 1.2-17.1, р=0.019 respectively). |
| format | Article |
| id | doaj-art-33cf85c7507145b69a0bbabca2b2959b |
| institution | DOAJ |
| issn | 2307-0404 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-33cf85c7507145b69a0bbabca2b2959b2025-08-20T02:50:41ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042020-12-0125412112710.26641/2307-0404.2020.4.221399221399Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in childrenT.R. Umanets0A.A. Buratynska1S.I. Tolkach2L.S. Stepanova3S.Yu. Matveeva4T.V. Kondratenkova5O.A. Smirnova6T.A. Garaschenko7V.F. Lapshyn8Yu.G. Antipkin9Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050The purpose of the study was to determine the risk factors affecting the development of asthma combined with gastroesophageal reflux disease (GERD). Seventy children aged 5-17 years with asthma were examined. They were divided to two groups: group 1 (50 children with asthma and GERD), and group 2 (20 children with isolated asthma). Medical history data were collected through specially designed questionnaire for parents. It was determined that the perinatal risk factors that likely contributed to developing co-morbid asthma and GERD were a threatened miscarriage (OR=6.65; 95% CI, 1.7-25.6, p=0.003), acute respiratory illnesses during pregnancy (OR=6.52; 95% CI, 1.4-31.2, p=0.008), polyhydramnios (p=0.039) and uterine inertia (p=0.0003). Food hypersensitivity in the first year of life, the severity of asthma in examined children played role in increasing the risk of developing asthma combined with GERD (OR=4.83; 95% CI, 1.3-18.6, p=0.013 and OR=4.45; 95% CI, 1.2-17.1, р=0.019 respectively).http://journals.uran.ua/index.php/2307-0404/article/view/221399children, asthma, gastroesophageal reflux disease, risk factors |
| spellingShingle | T.R. Umanets A.A. Buratynska S.I. Tolkach L.S. Stepanova S.Yu. Matveeva T.V. Kondratenkova O.A. Smirnova T.A. Garaschenko V.F. Lapshyn Yu.G. Antipkin Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children Medičnì Perspektivi children, asthma, gastroesophageal reflux disease, risk factors |
| title | Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children |
| title_full | Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children |
| title_fullStr | Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children |
| title_full_unstemmed | Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children |
| title_short | Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children |
| title_sort | impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children |
| topic | children, asthma, gastroesophageal reflux disease, risk factors |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/221399 |
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