MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment
The aim of review. To present up-to-date data on diagnostics and treatment of MALT-lymphoma of the stomach and experience of N.N.Burdenko Chief military clinical hospital in treatment of patients with this disease.Original positions. Not so long ago mucosa-associated lymphoid tumor was included in W...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2011-02-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1376 |
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| author | Ye. V. Ledin A. P. Seryakov V. L. Astashov |
| author_facet | Ye. V. Ledin A. P. Seryakov V. L. Astashov |
| author_sort | Ye. V. Ledin |
| collection | DOAJ |
| description | The aim of review. To present up-to-date data on diagnostics and treatment of MALT-lymphoma of the stomach and experience of N.N.Burdenko Chief military clinical hospital in treatment of patients with this disease.Original positions. Not so long ago mucosa-associated lymphoid tumor was included in WHO classification of hemopoietic and lymphoid tissues tumors, which is terminologically determined as extranodal marginal zone В-cellular lymphoma of the MALT-type. It is proved, that approximately 90% of cases of stomach МАLT-lymphomas are related to H. pylori infection. Despite the extensive data obtained for the last two decades on clinical and pathomorphologic properties of this disease, its molecular genetic features, optimal medical approach for this nosological entity it is not developed yet. It is especially actual for regional stages of disease. The article stresses therapeutic aspects: correspondence of treatment approach to disease stage, presence of Н. pylori infection, role of eradication and radiation therapy, surgery and chemotherapy. Basing on obtained data, original treatment algorithm was developed, which is proposed to application in clinical practice to provide optimal amount of medical care to the patient.Conclusion. Findings in MALT-lymphoma biology allowed to introduce new scientific and practical treatment projects in practice. |
| format | Article |
| id | doaj-art-33cadffbf8cc45439d2449d427fd0483 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2011-02-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-33cadffbf8cc45439d2449d427fd04832025-02-10T16:14:30ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732011-02-012116978931MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatmentYe. V. Ledin0A. P. Seryakov1V. L. Astashov2ФГУ «Главный военный клинический госпиталь им. Н.Н. Бурденко Минобороны России»ФГУ «Главный военный клинический госпиталь им. Н.Н. Бурденко Минобороны России»ФГУ «Главный военный клинический госпиталь им. Н.Н. Бурденко Минобороны России»The aim of review. To present up-to-date data on diagnostics and treatment of MALT-lymphoma of the stomach and experience of N.N.Burdenko Chief military clinical hospital in treatment of patients with this disease.Original positions. Not so long ago mucosa-associated lymphoid tumor was included in WHO classification of hemopoietic and lymphoid tissues tumors, which is terminologically determined as extranodal marginal zone В-cellular lymphoma of the MALT-type. It is proved, that approximately 90% of cases of stomach МАLT-lymphomas are related to H. pylori infection. Despite the extensive data obtained for the last two decades on clinical and pathomorphologic properties of this disease, its molecular genetic features, optimal medical approach for this nosological entity it is not developed yet. It is especially actual for regional stages of disease. The article stresses therapeutic aspects: correspondence of treatment approach to disease stage, presence of Н. pylori infection, role of eradication and radiation therapy, surgery and chemotherapy. Basing on obtained data, original treatment algorithm was developed, which is proposed to application in clinical practice to provide optimal amount of medical care to the patient.Conclusion. Findings in MALT-lymphoma biology allowed to introduce new scientific and practical treatment projects in practice.https://www.gastro-j.ru/jour/article/view/1376malt-lymphoma of the stomachh. pylori |
| spellingShingle | Ye. V. Ledin A. P. Seryakov V. L. Astashov MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment Российский журнал гастроэнтерологии, гепатологии, колопроктологии malt-lymphoma of the stomach h. pylori |
| title | MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment |
| title_full | MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment |
| title_fullStr | MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment |
| title_full_unstemmed | MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment |
| title_short | MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment |
| title_sort | malt lymphoma of the stomach clinical presentation diagnostics and treatment |
| topic | malt-lymphoma of the stomach h. pylori |
| url | https://www.gastro-j.ru/jour/article/view/1376 |
| work_keys_str_mv | AT yevledin maltlymphomaofthestomachclinicalpresentationdiagnosticsandtreatment AT apseryakov maltlymphomaofthestomachclinicalpresentationdiagnosticsandtreatment AT vlastashov maltlymphomaofthestomachclinicalpresentationdiagnosticsandtreatment |