Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth
Orthodontic treatment is increasingly popular as people worldwide seek esthetics and better quality of life. In orthodontic treatment, complex appliances and retainers are placed in the patients’ mouths for at least one year, which often lead to biofilm plaque accumulation. This in turn increases th...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2019/5602904 |
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| author | Li Cao Junling Wu Qiang Zhang Bashayer Baras Ghalia Bhadila Yuncong Li Mary Anne S. Melo Michael D. Weir Yuxing Bai Ning Zhang Hockin H. K. Xu |
| author_facet | Li Cao Junling Wu Qiang Zhang Bashayer Baras Ghalia Bhadila Yuncong Li Mary Anne S. Melo Michael D. Weir Yuxing Bai Ning Zhang Hockin H. K. Xu |
| author_sort | Li Cao |
| collection | DOAJ |
| description | Orthodontic treatment is increasingly popular as people worldwide seek esthetics and better quality of life. In orthodontic treatment, complex appliances and retainers are placed in the patients’ mouths for at least one year, which often lead to biofilm plaque accumulation. This in turn increases the caries-inducing bacteria, decreases the pH of the retained plaque on an enamel surface, and causes white spot lesions (WSLs) in enamel. This article reviews the cutting-edge research on a new class of bioactive and therapeutic dental resins, cements, and adhesives that can inhibit biofilms and protect tooth structures. The novel approaches include the use of protein-repellent and anticaries polymeric dental cements containing 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminododecyl methacrylate (DMAHDM); multifunctional resins that can inhibit enamel demineralization; protein-repellent and self-etching adhesives to greatly reduce oral biofilm growth; and novel polymethyl methacrylate resins to suppress oral biofilms and acid production. These new materials could reduce biofilm attachment, raise local biofilm pH, and facilitate the remineralization to protect the teeth. This novel class of dental resin with dual benefits of antibacterial and protein-repellent capabilities has the potential for a wide range of dental and biomedical applications to inhibit bacterial infection and protect the tissues. |
| format | Article |
| id | doaj-art-33c7326d8a664c48b9ebbb0e2782b19a |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-33c7326d8a664c48b9ebbb0e2782b19a2025-02-03T07:25:27ZengWileyInternational Journal of Polymer Science1687-94221687-94302019-01-01201910.1155/2019/56029045602904Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect TeethLi Cao0Junling Wu1Qiang Zhang2Bashayer Baras3Ghalia Bhadila4Yuncong Li5Mary Anne S. Melo6Michael D. Weir7Yuxing Bai8Ning Zhang9Hockin H. K. Xu10Department of Orthodontics, School of Stomatology, Capital Medical University, Beijing, ChinaDepartment of Prosthodontics, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan 250012, ChinaOral Implantology Center, Jinan Stomatological Hospital, Jinan 250001, ChinaDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland Dental School, Baltimore, MD 21201, USADepartment of Advanced Oral Sciences and Therapeutics, University of Maryland Dental School, Baltimore, MD 21201, USADepartment of Advanced Oral Sciences and Therapeutics, University of Maryland Dental School, Baltimore, MD 21201, USADepartment of Advanced Oral Sciences and Therapeutics, University of Maryland Dental School, Baltimore, MD 21201, USADepartment of Advanced Oral Sciences and Therapeutics, University of Maryland Dental School, Baltimore, MD 21201, USADepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing, ChinaDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing, ChinaDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland Dental School, Baltimore, MD 21201, USAOrthodontic treatment is increasingly popular as people worldwide seek esthetics and better quality of life. In orthodontic treatment, complex appliances and retainers are placed in the patients’ mouths for at least one year, which often lead to biofilm plaque accumulation. This in turn increases the caries-inducing bacteria, decreases the pH of the retained plaque on an enamel surface, and causes white spot lesions (WSLs) in enamel. This article reviews the cutting-edge research on a new class of bioactive and therapeutic dental resins, cements, and adhesives that can inhibit biofilms and protect tooth structures. The novel approaches include the use of protein-repellent and anticaries polymeric dental cements containing 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminododecyl methacrylate (DMAHDM); multifunctional resins that can inhibit enamel demineralization; protein-repellent and self-etching adhesives to greatly reduce oral biofilm growth; and novel polymethyl methacrylate resins to suppress oral biofilms and acid production. These new materials could reduce biofilm attachment, raise local biofilm pH, and facilitate the remineralization to protect the teeth. This novel class of dental resin with dual benefits of antibacterial and protein-repellent capabilities has the potential for a wide range of dental and biomedical applications to inhibit bacterial infection and protect the tissues.http://dx.doi.org/10.1155/2019/5602904 |
| spellingShingle | Li Cao Junling Wu Qiang Zhang Bashayer Baras Ghalia Bhadila Yuncong Li Mary Anne S. Melo Michael D. Weir Yuxing Bai Ning Zhang Hockin H. K. Xu Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth International Journal of Polymer Science |
| title | Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth |
| title_full | Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth |
| title_fullStr | Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth |
| title_full_unstemmed | Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth |
| title_short | Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth |
| title_sort | novel protein repellent and antibacterial resins and cements to inhibit lesions and protect teeth |
| url | http://dx.doi.org/10.1155/2019/5602904 |
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