The aging hematopoietic stem cell niche: a mini review
Hematopoietic stem cells (HSCs) undergo a functional decline during aging. The intrinsic characteristics of aged HSCs have been well-described and include a strong myeloid bias, an increase in total number, and a decrease in functionality during transplantation. The impact of the aged bone marrow mi...
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Main Authors: | Xin Gao, Jing Zhang, Owen J. Tamplin |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-02-01
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Series: | Frontiers in Hematology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/frhem.2025.1525132/full |
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