Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital
The most prevalent pathogens depend on the burn wound site, which reflects the hospital's nosocomial pathogens. Considering that burn wound infections, both endogenous and exogenous, continue to be the leading cause of disability and mortality across all age groups and in both developed and de...
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Action for Sustainable Efficacious Development and Awareness
2025-04-01
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| Series: | Environment Conservation Journal |
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| Online Access: | https://journal.environcj.in/index.php/ecj/article/view/2788 |
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| author | Nisha Devi Manjula Vagarali Lokjan Singh Anil Kumar Nishant Rai Manjusha Tyagi |
| author_facet | Nisha Devi Manjula Vagarali Lokjan Singh Anil Kumar Nishant Rai Manjusha Tyagi |
| author_sort | Nisha Devi |
| collection | DOAJ |
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The most prevalent pathogens depend on the burn wound site, which reflects the hospital's nosocomial pathogens. Considering that burn wound infections, both endogenous and exogenous, continue to be the leading cause of disability and mortality across all age groups and in both developed and developing nations, The antibiotic-resistant pattern of aerobic bacteria represents a vulnerable site for opportunistic colonization. The present study aimed at bacterial profiling and antimicrobial susceptibility patterns of isolates from burn wound infection in a tertiary care hospital. It was reported that thermal burns were 49.1%, electrical injuries were 37.4%, and scald burns were 13.5%. Among these, 38 (76%) were recognized as Gram-negative rods, and 12 (24%) were identified as Gram-positive cocci. Out of 38 pathogenic Gram-negative rods, 18 (47.36%) were Klebsiella pneumoniae, 10 (26.31%) were Pseudomonas aeruginosa, 4 (10.52%) were Acinetobacter species, 5 (13.15%) were Escherichia coli, and 1 (2.63%) was Citrobacter freundii. Out of 12 (24%) Gram-positive cocci, 9 (75%) coagulase. Negative Staphylococcus aureus (CONS), 2 (16.66%), Staphylococcus aureus, 1 (8.33%), and Enterococcus species were identified. In contrast, Staphylococcus aureus was 2 (4.4%) and Enterococcus species was 1 (2.2%). Staphylococcus aureus showed maximum sensitivity to chloramphenicol (C), clindamycin (CD), and vancomycin (VA). Chloramphenicol (23.9%) and tetracycline (19.5%) were effective drugs against Gram-negative organisms. The investigation revealed a wide variety of bacteria with markedly different resistance profiles, including both Gram-positive and Gram-negative organisms. Because of this intricacy, specific antimicrobial medications, depending on the features of each illness, are required.
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| format | Article |
| id | doaj-art-33be6a1ea44a427498018276b0d065bf |
| institution | DOAJ |
| issn | 0972-3099 2278-5124 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Action for Sustainable Efficacious Development and Awareness |
| record_format | Article |
| series | Environment Conservation Journal |
| spelling | doaj-art-33be6a1ea44a427498018276b0d065bf2025-08-20T03:22:44ZengAction for Sustainable Efficacious Development and AwarenessEnvironment Conservation Journal0972-30992278-51242025-04-0126210.36953/ECJ.27882849Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospitalNisha Devi0Manjula Vagarali1Lokjan Singh2Anil Kumar3Nishant Rai4Manjusha Tyagi5Department of Microbiology, Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana IndiaDepartment of Microbiology, Jawaharlal Nehru Medical College, KAHER, Belagavi, Karnataka, IndiaDepartment of Microbiology, Karnali Academy of Health Science, Teaching Hospital, Chandannath, Jumla, Karnali, NepalDepartment of Medical Laboratory Technology and Medical Microbiology, Sardar bhagwan Singh University, Balawala, Dehradun, Uttrakhand, IndiaDepartment of Biotechnology, Graphic Era (Deemed to be University), Clement Town, Dehradun, Uttrakhand, IndiaDepartment of Microbiology, SGRR University, Dehradun, Uttarakhand, India The most prevalent pathogens depend on the burn wound site, which reflects the hospital's nosocomial pathogens. Considering that burn wound infections, both endogenous and exogenous, continue to be the leading cause of disability and mortality across all age groups and in both developed and developing nations, The antibiotic-resistant pattern of aerobic bacteria represents a vulnerable site for opportunistic colonization. The present study aimed at bacterial profiling and antimicrobial susceptibility patterns of isolates from burn wound infection in a tertiary care hospital. It was reported that thermal burns were 49.1%, electrical injuries were 37.4%, and scald burns were 13.5%. Among these, 38 (76%) were recognized as Gram-negative rods, and 12 (24%) were identified as Gram-positive cocci. Out of 38 pathogenic Gram-negative rods, 18 (47.36%) were Klebsiella pneumoniae, 10 (26.31%) were Pseudomonas aeruginosa, 4 (10.52%) were Acinetobacter species, 5 (13.15%) were Escherichia coli, and 1 (2.63%) was Citrobacter freundii. Out of 12 (24%) Gram-positive cocci, 9 (75%) coagulase. Negative Staphylococcus aureus (CONS), 2 (16.66%), Staphylococcus aureus, 1 (8.33%), and Enterococcus species were identified. In contrast, Staphylococcus aureus was 2 (4.4%) and Enterococcus species was 1 (2.2%). Staphylococcus aureus showed maximum sensitivity to chloramphenicol (C), clindamycin (CD), and vancomycin (VA). Chloramphenicol (23.9%) and tetracycline (19.5%) were effective drugs against Gram-negative organisms. The investigation revealed a wide variety of bacteria with markedly different resistance profiles, including both Gram-positive and Gram-negative organisms. Because of this intricacy, specific antimicrobial medications, depending on the features of each illness, are required. https://journal.environcj.in/index.php/ecj/article/view/2788ChloramphenicolClinical and laboratory standards instituteCoagulase-negative Staphylococcus aureusKlebsiella pneumoniaeRadiation |
| spellingShingle | Nisha Devi Manjula Vagarali Lokjan Singh Anil Kumar Nishant Rai Manjusha Tyagi Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital Environment Conservation Journal Chloramphenicol Clinical and laboratory standards institute Coagulase-negative Staphylococcus aureus Klebsiella pneumoniae Radiation |
| title | Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital |
| title_full | Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital |
| title_fullStr | Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital |
| title_full_unstemmed | Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital |
| title_short | Bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital |
| title_sort | bacterial profile and antimicrobial susceptibility patterns of isolates from burn wound infection at tertiary care hospital |
| topic | Chloramphenicol Clinical and laboratory standards institute Coagulase-negative Staphylococcus aureus Klebsiella pneumoniae Radiation |
| url | https://journal.environcj.in/index.php/ecj/article/view/2788 |
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