BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKEN
The aim of the study was to establish the structural organization of the blood-brain barrier of the brainstem capillaries of domestic chicken. The material used for the study was fragments of the brainstem tissue of the White Loman cross chicken. Their fixation and further processing to produce ult...
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| Format: | Article |
| Language: | English |
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Scientific Veterinary Institute “Novi Sad”
2025-05-01
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| Series: | Archives of Veterinary Medicine |
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| Online Access: | https://niv.ns.ac.rs/e-avm/index.php/e-avm/article/view/404 |
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| author | Vladimir Ponamarev Alexey Prusakov |
| author_facet | Vladimir Ponamarev Alexey Prusakov |
| author_sort | Vladimir Ponamarev |
| collection | DOAJ |
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The aim of the study was to establish the structural organization of the blood-brain barrier of the brainstem capillaries of domestic chicken. The material used for the study was fragments of the brainstem tissue of the White Loman cross chicken. Their fixation and further processing to produce ultrathin sections were carried out in accordance with generally accepted methods. The obtained sections were examined using an electron microscope Jem-1011. The manuscript was written using the terminology of the International Histological Nomenclature. It was established that the brainstem blood-brain barrier of domestic chicken is formed by four structural elements: endothelial cells, basal membrane, pericytes, and processes of glial cells in astrocytes. The endotheliocytes that form the lumen of the capillaries are in contact using tight junctions, preventing the possibility of large molecular compounds to penetrate the blood-brain barrier. If there are pericytes accompanying the capillary, they are surrounded by cleavages of their basal membrane. The latter form a single layer along the capillaries, surrounding their wall from the outside. These structures ensure the selective transport of substances from the bloodstream to the nervous tissue.
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| format | Article |
| id | doaj-art-33bbbafeeeac422db931691c96cb2205 |
| institution | Kabale University |
| issn | 1820-9955 2683-4138 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Scientific Veterinary Institute “Novi Sad” |
| record_format | Article |
| series | Archives of Veterinary Medicine |
| spelling | doaj-art-33bbbafeeeac422db931691c96cb22052025-08-20T03:47:32ZengScientific Veterinary Institute “Novi Sad”Archives of Veterinary Medicine1820-99552683-41382025-05-0118110.46784/e-avm.v18i1.404BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKENVladimir Ponamarev0Alexey Prusakov 1Federal State Budgetary Educational Institution of Higher Education “Saint Petersburg State University of Veterinary Medicine”Federal State Budgetary Educational Institution of Higher Education “Saint-Petersburg State University of Veterinary Medicine”, Russia, Saint Petersburg The aim of the study was to establish the structural organization of the blood-brain barrier of the brainstem capillaries of domestic chicken. The material used for the study was fragments of the brainstem tissue of the White Loman cross chicken. Their fixation and further processing to produce ultrathin sections were carried out in accordance with generally accepted methods. The obtained sections were examined using an electron microscope Jem-1011. The manuscript was written using the terminology of the International Histological Nomenclature. It was established that the brainstem blood-brain barrier of domestic chicken is formed by four structural elements: endothelial cells, basal membrane, pericytes, and processes of glial cells in astrocytes. The endotheliocytes that form the lumen of the capillaries are in contact using tight junctions, preventing the possibility of large molecular compounds to penetrate the blood-brain barrier. If there are pericytes accompanying the capillary, they are surrounded by cleavages of their basal membrane. The latter form a single layer along the capillaries, surrounding their wall from the outside. These structures ensure the selective transport of substances from the bloodstream to the nervous tissue. https://niv.ns.ac.rs/e-avm/index.php/e-avm/article/view/404neurologybrainhistohematic barriersblood-brain barrierhomeostasis |
| spellingShingle | Vladimir Ponamarev Alexey Prusakov BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKEN Archives of Veterinary Medicine neurology brain histohematic barriers blood-brain barrier homeostasis |
| title | BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKEN |
| title_full | BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKEN |
| title_fullStr | BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKEN |
| title_full_unstemmed | BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKEN |
| title_short | BLOOD-BRAIN BARRIER OF CAPILLARIES OF THE BRAINSTEM OF DOMESTIC CHICKEN |
| title_sort | blood brain barrier of capillaries of the brainstem of domestic chicken |
| topic | neurology brain histohematic barriers blood-brain barrier homeostasis |
| url | https://niv.ns.ac.rs/e-avm/index.php/e-avm/article/view/404 |
| work_keys_str_mv | AT vladimirponamarev bloodbrainbarrierofcapillariesofthebrainstemofdomesticchicken AT alexeyprusakov bloodbrainbarrierofcapillariesofthebrainstemofdomesticchicken |