Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical Trial
Harmony between facial complexion and gingival health goes hand in hand. Gingival depigmentation is an aesthetic correction of hyperactive melanocytes in gingival tissues that lead to hyperpigmentation. Current study compares depigmentation, pain scores, and itching with scalpel technique and nonsur...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-01-01
|
| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2023/4586923 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849305975452860416 |
|---|---|
| author | Dhanashree S. Chaudhary Simran R. Parwani Shital Barkhade Minal Gajbhiye Rajkumar Parwani Geetanjali Sikka Kshipra Kawadkar Nishita Jaju Soni Niccolò Giuseppe Armogida Himanshu Dadlani Gianrico Spagnuolo |
| author_facet | Dhanashree S. Chaudhary Simran R. Parwani Shital Barkhade Minal Gajbhiye Rajkumar Parwani Geetanjali Sikka Kshipra Kawadkar Nishita Jaju Soni Niccolò Giuseppe Armogida Himanshu Dadlani Gianrico Spagnuolo |
| author_sort | Dhanashree S. Chaudhary |
| collection | DOAJ |
| description | Harmony between facial complexion and gingival health goes hand in hand. Gingival depigmentation is an aesthetic correction of hyperactive melanocytes in gingival tissues that lead to hyperpigmentation. Current study compares depigmentation, pain scores, and itching with scalpel technique and nonsurgical intramucosal Vitamin C injection. 30 individuals in the age range of 18–40 years conscious of dark gums were randomly allocated to test and control group by lottery method. Thorough Phase I therapy was performed one week before the procedure. Area and intensity of depigmentation were evaluated preoperatively and postoperatively; pain score, itching, and repigmentation percentage were the postoperative parameters. After 24 hrs, test group showed significantly lesser VAS score for pain as compared to control group. There was no statistically significant difference in preoperative area of pigmentation between the test and control group (p=0.936). Postoperatively also, there was no statistically significant difference in area of pigmentation between the test and control group (p=0.932). For comparing area of pigmentation, an independent t-test was applied and Mann–Whitney test was used for differentiating the intensity of pigmentation, repigmentation, and VAS score between the groups. The study concluded that Vitamin C mesotherapy and scalpel technique showed comparable results in reduction of areas and intensity of gingival hyperpigmentation. |
| format | Article |
| id | doaj-art-33b38fe35e7e414087b5c9d28ef8848a |
| institution | Kabale University |
| issn | 1687-8736 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-33b38fe35e7e414087b5c9d28ef8848a2025-08-20T03:55:15ZengWileyInternational Journal of Dentistry1687-87362023-01-01202310.1155/2023/4586923Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical TrialDhanashree S. Chaudhary0Simran R. Parwani1Shital Barkhade2Minal Gajbhiye3Rajkumar Parwani4Geetanjali Sikka5Kshipra Kawadkar6Nishita Jaju Soni7Niccolò Giuseppe Armogida8Himanshu Dadlani9Gianrico Spagnuolo10Department of PeriodontologyDepartment of PeriodontologyDepartment of PeriodontologyDepartment of PeriodontologyDepartment of Oral PathologyDepartment of PeriodontologyDepartment of PeriodontologyDepartment of PeriodontologyDepartment of NeurosciencesDepartment of PeriodontologyDepartment of NeurosciencesHarmony between facial complexion and gingival health goes hand in hand. Gingival depigmentation is an aesthetic correction of hyperactive melanocytes in gingival tissues that lead to hyperpigmentation. Current study compares depigmentation, pain scores, and itching with scalpel technique and nonsurgical intramucosal Vitamin C injection. 30 individuals in the age range of 18–40 years conscious of dark gums were randomly allocated to test and control group by lottery method. Thorough Phase I therapy was performed one week before the procedure. Area and intensity of depigmentation were evaluated preoperatively and postoperatively; pain score, itching, and repigmentation percentage were the postoperative parameters. After 24 hrs, test group showed significantly lesser VAS score for pain as compared to control group. There was no statistically significant difference in preoperative area of pigmentation between the test and control group (p=0.936). Postoperatively also, there was no statistically significant difference in area of pigmentation between the test and control group (p=0.932). For comparing area of pigmentation, an independent t-test was applied and Mann–Whitney test was used for differentiating the intensity of pigmentation, repigmentation, and VAS score between the groups. The study concluded that Vitamin C mesotherapy and scalpel technique showed comparable results in reduction of areas and intensity of gingival hyperpigmentation.http://dx.doi.org/10.1155/2023/4586923 |
| spellingShingle | Dhanashree S. Chaudhary Simran R. Parwani Shital Barkhade Minal Gajbhiye Rajkumar Parwani Geetanjali Sikka Kshipra Kawadkar Nishita Jaju Soni Niccolò Giuseppe Armogida Himanshu Dadlani Gianrico Spagnuolo Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical Trial International Journal of Dentistry |
| title | Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical Trial |
| title_full | Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical Trial |
| title_fullStr | Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical Trial |
| title_full_unstemmed | Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical Trial |
| title_short | Physiological Gingival Melanin Hyperpigmentation Treatment with Injectable Vitamin C and Scalpel Technique: A Randomised Controlled Clinical Trial |
| title_sort | physiological gingival melanin hyperpigmentation treatment with injectable vitamin c and scalpel technique a randomised controlled clinical trial |
| url | http://dx.doi.org/10.1155/2023/4586923 |
| work_keys_str_mv | AT dhanashreeschaudhary physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT simranrparwani physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT shitalbarkhade physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT minalgajbhiye physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT rajkumarparwani physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT geetanjalisikka physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT kshiprakawadkar physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT nishitajajusoni physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT niccologiuseppearmogida physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT himanshudadlani physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial AT gianricospagnuolo physiologicalgingivalmelaninhyperpigmentationtreatmentwithinjectablevitamincandscalpeltechniquearandomisedcontrolledclinicaltrial |