COVID-19 vaccination: challenges in the pediatric population
Vaccination is considered to be one of the most effective means of protecting individuals and populations from the risks associated with exposure to various pathogens. The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affected people of all ages world...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1390951/full |
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| author | Alice Nicoleta Azoicai Ingrith Miron Ancuta Lupu Monica Mihaela Alexoae Iuliana Magdalena Starcea Mirabela Alecsa Vasile Valeriu Lupu Ciprian Danielescu Alin Horatiu Nedelcu Delia Lidia Salaru Felicia Dragan Ileana Ioniuc |
| author_facet | Alice Nicoleta Azoicai Ingrith Miron Ancuta Lupu Monica Mihaela Alexoae Iuliana Magdalena Starcea Mirabela Alecsa Vasile Valeriu Lupu Ciprian Danielescu Alin Horatiu Nedelcu Delia Lidia Salaru Felicia Dragan Ileana Ioniuc |
| author_sort | Alice Nicoleta Azoicai |
| collection | DOAJ |
| description | Vaccination is considered to be one of the most effective means of protecting individuals and populations from the risks associated with exposure to various pathogens. The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affected people of all ages worldwide. In response, several pharmaceutical companies rapidly leveraged their resources to develop vaccines within a very short period of time, leading to the introduction of new, improved, and combination vaccines for community-wide immunization. This review aims to provide a summary of the available literature on the efficacy and safety of COVID-19 vaccines in the pediatric population ranging from 0 to 18 years. An analysis of recent published studies reveals that the majority of clinical trials have reported a sustained immune response following COVID-19 vaccination in children across various age groups worldwide. The majority of the authors highlighted the effectiveness and safety of immunization schedules in children and adolescents. The population-level efficacy of this vaccination remains to be determined, provided that the benefits outweigh the potential risks. Long-term side effects must still be monitored to enable the development of safer and more effective vaccines for future pandemics. |
| format | Article |
| id | doaj-art-33a8fd64c4444441b608ff481411fd7e |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj-art-33a8fd64c4444441b608ff481411fd7e2025-01-29T06:45:49ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011210.3389/fpubh.2024.13909511390951COVID-19 vaccination: challenges in the pediatric populationAlice Nicoleta Azoicai0Ingrith Miron1Ancuta Lupu2Monica Mihaela Alexoae3Iuliana Magdalena Starcea4Mirabela Alecsa5Vasile Valeriu Lupu6Ciprian Danielescu7Alin Horatiu Nedelcu8Delia Lidia Salaru9Felicia Dragan10Ileana Ioniuc11Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaFaculty of Medicine and Pharmacy, University of Oradea, Oradea, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, RomaniaVaccination is considered to be one of the most effective means of protecting individuals and populations from the risks associated with exposure to various pathogens. The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affected people of all ages worldwide. In response, several pharmaceutical companies rapidly leveraged their resources to develop vaccines within a very short period of time, leading to the introduction of new, improved, and combination vaccines for community-wide immunization. This review aims to provide a summary of the available literature on the efficacy and safety of COVID-19 vaccines in the pediatric population ranging from 0 to 18 years. An analysis of recent published studies reveals that the majority of clinical trials have reported a sustained immune response following COVID-19 vaccination in children across various age groups worldwide. The majority of the authors highlighted the effectiveness and safety of immunization schedules in children and adolescents. The population-level efficacy of this vaccination remains to be determined, provided that the benefits outweigh the potential risks. Long-term side effects must still be monitored to enable the development of safer and more effective vaccines for future pandemics.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1390951/fullvaccineCOVID-19SARS-CoV-2efficacysafetychildren |
| spellingShingle | Alice Nicoleta Azoicai Ingrith Miron Ancuta Lupu Monica Mihaela Alexoae Iuliana Magdalena Starcea Mirabela Alecsa Vasile Valeriu Lupu Ciprian Danielescu Alin Horatiu Nedelcu Delia Lidia Salaru Felicia Dragan Ileana Ioniuc COVID-19 vaccination: challenges in the pediatric population Frontiers in Public Health vaccine COVID-19 SARS-CoV-2 efficacy safety children |
| title | COVID-19 vaccination: challenges in the pediatric population |
| title_full | COVID-19 vaccination: challenges in the pediatric population |
| title_fullStr | COVID-19 vaccination: challenges in the pediatric population |
| title_full_unstemmed | COVID-19 vaccination: challenges in the pediatric population |
| title_short | COVID-19 vaccination: challenges in the pediatric population |
| title_sort | covid 19 vaccination challenges in the pediatric population |
| topic | vaccine COVID-19 SARS-CoV-2 efficacy safety children |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1390951/full |
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