A critical review of outcomes of cancer during the COVID-19 pandemic

The recent outbreak of COVID-19 has created an alarming fear, apprehension, and worry world over. Cancer patients represent a subgroup that is vulnerable and is under high risk. It is, therefore, necessary to analyze factors that predict outcomes in these patients so that they can be triaged accordi...

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Main Authors: Florida Sharin, Arjun G Singh, Burhanuddin Qayyumi, Pankaj Chaturvedi
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=4;spage=461;epage=467;aulast=Sharin
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author Florida Sharin
Arjun G Singh
Burhanuddin Qayyumi
Pankaj Chaturvedi
author_facet Florida Sharin
Arjun G Singh
Burhanuddin Qayyumi
Pankaj Chaturvedi
author_sort Florida Sharin
collection DOAJ
description The recent outbreak of COVID-19 has created an alarming fear, apprehension, and worry world over. Cancer patients represent a subgroup that is vulnerable and is under high risk. It is, therefore, necessary to analyze factors that predict outcomes in these patients so that they can be triaged accordingly in order to mitigate the effects of COVID-19 on cancer management. To determine the factors affecting cancer patients in COVID-19. A systematic search was performed to identify all relevant studies on PubMed, Embase, and Google Scholar published until April 5, 2020. Relevant articles that reported the incidence, demographic and clinical characteristics, treatment, and outcomes of cancer patients infected by COVID-19 were included in the analysis. Among 559 articles that were further screened, 14 articles fulfilled the inclusion criteria. The incidence of cancer across various studies ranged from 0.5% to 2.43%. Males were more than females, and the mean age affected was 63.1–66 years. Lung cancer was the most common subtype (25%–58.3%). Cancer patients, as reported, had a higher risk of progressing to severe events (hazard ratio:3.56, 95% confidence interval: 1.65–7.69; P < 0.0001). Nearly 39%–53.6% of patients who had a recent history of anticancer therapy developed severe events. Individuals with cancer feared the risk of complications. Cancer patients have worse outcomes from COVID-19, compared to the general population, providing a reason to pay more timely attention. High-risk patients should have vigorous screening and intensive surveillance. Anticancer treatment during COVID-19 should be modified based on the type and prognosis of cancer.
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spelling doaj-art-33a22d5680c840a284efa5fc32b25bbb2025-08-20T02:01:50ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292020-01-0141446146710.4103/ijmpo.ijmpo_187_20A critical review of outcomes of cancer during the COVID-19 pandemicFlorida SharinArjun G SinghBurhanuddin QayyumiPankaj ChaturvediThe recent outbreak of COVID-19 has created an alarming fear, apprehension, and worry world over. Cancer patients represent a subgroup that is vulnerable and is under high risk. It is, therefore, necessary to analyze factors that predict outcomes in these patients so that they can be triaged accordingly in order to mitigate the effects of COVID-19 on cancer management. To determine the factors affecting cancer patients in COVID-19. A systematic search was performed to identify all relevant studies on PubMed, Embase, and Google Scholar published until April 5, 2020. Relevant articles that reported the incidence, demographic and clinical characteristics, treatment, and outcomes of cancer patients infected by COVID-19 were included in the analysis. Among 559 articles that were further screened, 14 articles fulfilled the inclusion criteria. The incidence of cancer across various studies ranged from 0.5% to 2.43%. Males were more than females, and the mean age affected was 63.1–66 years. Lung cancer was the most common subtype (25%–58.3%). Cancer patients, as reported, had a higher risk of progressing to severe events (hazard ratio:3.56, 95% confidence interval: 1.65–7.69; P < 0.0001). Nearly 39%–53.6% of patients who had a recent history of anticancer therapy developed severe events. Individuals with cancer feared the risk of complications. Cancer patients have worse outcomes from COVID-19, compared to the general population, providing a reason to pay more timely attention. High-risk patients should have vigorous screening and intensive surveillance. Anticancer treatment during COVID-19 should be modified based on the type and prognosis of cancer.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=4;spage=461;epage=467;aulast=Sharincancercovid-19malignancysevere acute respiratory syndrome-related coronavirus
spellingShingle Florida Sharin
Arjun G Singh
Burhanuddin Qayyumi
Pankaj Chaturvedi
A critical review of outcomes of cancer during the COVID-19 pandemic
Indian Journal of Medical and Paediatric Oncology
cancer
covid-19
malignancy
severe acute respiratory syndrome-related coronavirus
title A critical review of outcomes of cancer during the COVID-19 pandemic
title_full A critical review of outcomes of cancer during the COVID-19 pandemic
title_fullStr A critical review of outcomes of cancer during the COVID-19 pandemic
title_full_unstemmed A critical review of outcomes of cancer during the COVID-19 pandemic
title_short A critical review of outcomes of cancer during the COVID-19 pandemic
title_sort critical review of outcomes of cancer during the covid 19 pandemic
topic cancer
covid-19
malignancy
severe acute respiratory syndrome-related coronavirus
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=4;spage=461;epage=467;aulast=Sharin
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