Head-to-Head: Recombinant Human Prourokinase Versus Intravenous Thrombolytics in Acute Ischemic Stroke Within 4.5 Hours – A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials

Head-to-Head: Recombinant Human Prourokinase Versus Intravenous Thrombolytics in Acute Ischemic Stroke Within 4.5 Hours – A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials

Background Intravenous thrombolytics are essential for achieving timely reperfusion in acute ischemic stroke (AIS), with alteplase historically serving as the standard of care. Emerging alternatives like recombinant human prourokinase (rhPro-UK), reteplase, and tenecteplase offer potential improveme...

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Main Authors: Muhammad Hassan Waseem MBBS, Zain ul Abideen MBBS, Areeba Shoaib MBBS, Muhammad Osama MBBS, Muhammad Abdullah Ali MBBS, Sania Aimen MBBS, Muhammad Wajih Ansari MD, Rowaid Ahmad MD, Muhammad Arslan Tariq MD, Ameer Haider Cheema MD, Aleeza Afzal MBBS, Pawan Kumar Thada MBBS
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296251334563
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