Establishment of a zebrafish map3k15knockout line using CRISPR/Cas9 gene editing technology

Objective To establish a homozygous zebrafish map3k15 knockout line using CRISPR/Cas9 gene editing technology so to provide an animal model for investigation of potential role of map3k15 in renal diseases. Methods 1)Analyzing the expression pattern of map3k15 in zebrafish; 2)Establishing a homozygou...

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Bibliographic Details
Main Author: JIA Chunyu, SHEN Yan, CHEN Gang, ZHENG Ke, QIN Yan, LI Xuemei
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2025-03-01
Series:Jichu yixue yu linchuang
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Online Access:https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-3-281-290.pdf
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