Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma

Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma

Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most common malignant urological tumor, and regrettably, and is insensitive to chemotherapy and radiotherapy, resulting in poor patient outcomes. DBF4 plays a critical role in DNA replication and participates in various biological fu...

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Bibliographic Details
Main Authors: Liuyan Chen, Lvying Wu, Minying Tang, Yuanhang Cheng, Kuanyin Wang, Jianan Zhang, Wenyi Deng, Lingfeng Zhu, Jin Chen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Urology
Subjects:
DBF4
Clear cell renal cell carcinoma
Renal cell carcinoma
CDC7
Biomarker
Online Access:https://doi.org/10.1186/s12894-025-01694-x
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