Global translational impacts of the loss of the tRNA modification t6A in yeast
The universal tRNA modification t6A is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of t6A37 leads to severe growth defects in baker’s yeast, phenotypes similar to those caused by defects in mcm5s2U34 synthesis. Mutants in mcm5s2U34 can be suppressed by overexpression of...
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| Main Authors: | Patrick C. Thiaville, Rachel Legendre, Diego Rojas-Benítez, Agnès Baudin-Baillieu, Isabelle Hatin, Guilhem Chalancon, Alvaro Glavic, Olivier Namy, Valérie de Crécy-Lagard |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Shared Science Publishers OG
2015-12-01
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| Series: | Microbial Cell |
| Subjects: | |
| Online Access: | http://microbialcell.com/researcharticles/global-translational-impacts-of-the-loss-of-the-trna-modification-t6a-in-yeast/ |
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