Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study

Background. Fasting during the lunar month of Ramadan is mandatory to all healthy adult Muslims. Renal transplant recipients are often worried about the impact of fluid and electrolyte deprivation during fasting on the function of their allograft. We aimed to examine the effect of fasting Ramadan on...

Full description

Saved in:
Bibliographic Details
Main Authors: Ihab A. Ibrahim, Ehab A. Hassan, Abdelrahman M. Alkhan, Mohamed A. Hussein, Ahmed F. Alhabashi, Tariq Z. Ali, Yasir Z. Shah, Ibrahim S. Alahmadi, Mohamed S. Abdelsalam, Mohamed E. Rashwan, Ammar Abdulbaki, Dieter C. Broering, Hassan A. Aleid
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2018/4890978
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850157098233495552
author Ihab A. Ibrahim
Ehab A. Hassan
Abdelrahman M. Alkhan
Mohamed A. Hussein
Ahmed F. Alhabashi
Tariq Z. Ali
Yasir Z. Shah
Ibrahim S. Alahmadi
Mohamed S. Abdelsalam
Mohamed E. Rashwan
Ammar Abdulbaki
Dieter C. Broering
Hassan A. Aleid
author_facet Ihab A. Ibrahim
Ehab A. Hassan
Abdelrahman M. Alkhan
Mohamed A. Hussein
Ahmed F. Alhabashi
Tariq Z. Ali
Yasir Z. Shah
Ibrahim S. Alahmadi
Mohamed S. Abdelsalam
Mohamed E. Rashwan
Ammar Abdulbaki
Dieter C. Broering
Hassan A. Aleid
author_sort Ihab A. Ibrahim
collection DOAJ
description Background. Fasting during the lunar month of Ramadan is mandatory to all healthy adult Muslims. Renal transplant recipients are often worried about the impact of fluid and electrolyte deprivation during fasting on the function of their allograft. We aimed to examine the effect of fasting Ramadan on the graft function in renal transplant recipients. Methods. This retrospective cohort study included patients who underwent kidney transplantation in our tertiary referral center. Baseline pre-Ramadan estimated glomerular filtration rate (eGFR), mean arterial pressure (MAP), and urinary protein excretion were compared to those during and after Ramadan within and between the fasting and non-fasting groups. Results. The study population included 280 kidney transplant recipients who chose to fast during the Ramadan month (June-July 2014) and 285 recipients who did not fast. In the fasting group, baseline eGFR did not change from that during or post-Ramadan (72.6±23.7 versus 72.3±24.5 mL/min/1.73 m2, P=0.53; and 72.6±23.7 versus 72±23.2 mL/min/1.73 m2, P=0.14, respectively). Compared to baseline, there were no significant differences between the fasting and the non-fasting groups in terms of mean percent changes in eGFR, MAP, and urinary protein excretion. Conclusion. Fasting during the month of Ramadan did not have significant adverse effects on renal allograft function.
format Article
id doaj-art-337ca9548ecc4912b1f807aad4018f6a
institution OA Journals
issn 2090-0007
2090-0015
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Journal of Transplantation
spelling doaj-art-337ca9548ecc4912b1f807aad4018f6a2025-08-20T02:24:17ZengWileyJournal of Transplantation2090-00072090-00152018-01-01201810.1155/2018/48909784890978Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective StudyIhab A. Ibrahim0Ehab A. Hassan1Abdelrahman M. Alkhan2Mohamed A. Hussein3Ahmed F. Alhabashi4Tariq Z. Ali5Yasir Z. Shah6Ibrahim S. Alahmadi7Mohamed S. Abdelsalam8Mohamed E. Rashwan9Ammar Abdulbaki10Dieter C. Broering11Hassan A. Aleid12Department of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaOrgan Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaDepartment of Kidney and Pancreas Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaBackground. Fasting during the lunar month of Ramadan is mandatory to all healthy adult Muslims. Renal transplant recipients are often worried about the impact of fluid and electrolyte deprivation during fasting on the function of their allograft. We aimed to examine the effect of fasting Ramadan on the graft function in renal transplant recipients. Methods. This retrospective cohort study included patients who underwent kidney transplantation in our tertiary referral center. Baseline pre-Ramadan estimated glomerular filtration rate (eGFR), mean arterial pressure (MAP), and urinary protein excretion were compared to those during and after Ramadan within and between the fasting and non-fasting groups. Results. The study population included 280 kidney transplant recipients who chose to fast during the Ramadan month (June-July 2014) and 285 recipients who did not fast. In the fasting group, baseline eGFR did not change from that during or post-Ramadan (72.6±23.7 versus 72.3±24.5 mL/min/1.73 m2, P=0.53; and 72.6±23.7 versus 72±23.2 mL/min/1.73 m2, P=0.14, respectively). Compared to baseline, there were no significant differences between the fasting and the non-fasting groups in terms of mean percent changes in eGFR, MAP, and urinary protein excretion. Conclusion. Fasting during the month of Ramadan did not have significant adverse effects on renal allograft function.http://dx.doi.org/10.1155/2018/4890978
spellingShingle Ihab A. Ibrahim
Ehab A. Hassan
Abdelrahman M. Alkhan
Mohamed A. Hussein
Ahmed F. Alhabashi
Tariq Z. Ali
Yasir Z. Shah
Ibrahim S. Alahmadi
Mohamed S. Abdelsalam
Mohamed E. Rashwan
Ammar Abdulbaki
Dieter C. Broering
Hassan A. Aleid
Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study
Journal of Transplantation
title Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study
title_full Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study
title_fullStr Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study
title_full_unstemmed Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study
title_short Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study
title_sort ramadan fasting in kidney transplant recipients a single centre retrospective study
url http://dx.doi.org/10.1155/2018/4890978
work_keys_str_mv AT ihabaibrahim ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT ehabahassan ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT abdelrahmanmalkhan ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT mohamedahussein ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT ahmedfalhabashi ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT tariqzali ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT yasirzshah ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT ibrahimsalahmadi ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT mohamedsabdelsalam ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT mohamederashwan ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT ammarabdulbaki ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT dietercbroering ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy
AT hassanaaleid ramadanfastinginkidneytransplantrecipientsasinglecentreretrospectivestudy