Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis

Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opi...

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Main Authors: Konstantinos A. Kontoangelos, Anastasios V. Kouzoupis, Panagiotis P. Ferentinos, Ioannis D. Xynos, Nikolaos V. Sipsas, George N. Papadimitriou
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2013/912409
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author Konstantinos A. Kontoangelos
Anastasios V. Kouzoupis
Panagiotis P. Ferentinos
Ioannis D. Xynos
Nikolaos V. Sipsas
George N. Papadimitriou
author_facet Konstantinos A. Kontoangelos
Anastasios V. Kouzoupis
Panagiotis P. Ferentinos
Ioannis D. Xynos
Nikolaos V. Sipsas
George N. Papadimitriou
author_sort Konstantinos A. Kontoangelos
collection DOAJ
description Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opioids, we administered pregabalin at a dose of 300 mg as an analgesic agent while opioids were discontinued. Findings. Pain symptoms improved progressively, and opioids were gradually discontinued without any withdrawal symptoms reported. Conclusions. Pregabalin is potentially useful in the management of pain in patients with AS while effectively managing the discontinuation of opioid treatment.
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publisher Wiley
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series Case Reports in Psychiatry
spelling doaj-art-33674a05524b4367ad053552cdd0d5d42025-02-03T05:46:19ZengWileyCase Reports in Psychiatry2090-682X2090-68382013-01-01201310.1155/2013/912409912409Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing SpondylitisKonstantinos A. Kontoangelos0Anastasios V. Kouzoupis1Panagiotis P. Ferentinos2Ioannis D. Xynos3Nikolaos V. Sipsas4George N. Papadimitriou51st Department of Psychiatry, Eginition Hospital, Athens University Medical School, 74 Vas Sofias Avenue, 11528 Athens, Greece1st Department of Psychiatry, Eginition Hospital, Athens University Medical School, 74 Vas Sofias Avenue, 11528 Athens, Greece1st Department of Psychiatry, Eginition Hospital, Athens University Medical School, 74 Vas Sofias Avenue, 11528 Athens, GreecePathophysiology Department, Laikon General Hospital, Athens University Medical School, 11528 Athens, GreecePathophysiology Department, Laikon General Hospital, Athens University Medical School, 11528 Athens, Greece1st Department of Psychiatry, Eginition Hospital, Athens University Medical School, 74 Vas Sofias Avenue, 11528 Athens, GreeceBackground. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opioids, we administered pregabalin at a dose of 300 mg as an analgesic agent while opioids were discontinued. Findings. Pain symptoms improved progressively, and opioids were gradually discontinued without any withdrawal symptoms reported. Conclusions. Pregabalin is potentially useful in the management of pain in patients with AS while effectively managing the discontinuation of opioid treatment.http://dx.doi.org/10.1155/2013/912409
spellingShingle Konstantinos A. Kontoangelos
Anastasios V. Kouzoupis
Panagiotis P. Ferentinos
Ioannis D. Xynos
Nikolaos V. Sipsas
George N. Papadimitriou
Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis
Case Reports in Psychiatry
title Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis
title_full Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis
title_fullStr Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis
title_full_unstemmed Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis
title_short Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis
title_sort pregabalin for opioid refractory pain in a patient with ankylosing spondylitis
url http://dx.doi.org/10.1155/2013/912409
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