RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERY
Conventional drug delivery systems can be inadequate in many areas today due to limiting factors such as the narrow therapeutic window, complex dosing interval in long-term treatments, and systemic toxicity. Accordingly, a search has been carried out for new controlled drug delivery systems, which a...
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Istanbul University Press
2022-06-01
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| Series: | Sabiad |
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| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/D49E40C0EBF54160B9E7D3B962A44EBF |
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| author | Esher Özçelik Meryem Sedef Erdal Yıldız Özsoy Erginer |
| author_facet | Esher Özçelik Meryem Sedef Erdal Yıldız Özsoy Erginer |
| author_sort | Esher Özçelik |
| collection | DOAJ |
| description | Conventional drug delivery systems can be inadequate in many areas today due to limiting factors such as the narrow therapeutic window, complex dosing interval in long-term treatments, and systemic toxicity. Accordingly, a search has been carried out for new controlled drug delivery systems, which aim to localize the pharmacological activity of the drug to the desired area at the desired rate, and exhibit increased activity with less complications for more drugs. Better patient compliance can be achieved with microfluidic-based drug delivery systems, which have been developed to meet these needs, and better release control can be achieved with advanced drug applications. These systems, created by the control and manipulation of nano/micro-sized liquids, have taken their place in the controlled release platform with a unique character on a single chip. This review provides general information about controlled drug release, then discusses biomedical devices, one of the new technologies developed through advancing research, and the microfluidic devices (micropumps and microneedles) that they utilize. Their types, structures, properties, preparation techniques, where they can be used and related applications, the advantages they can bring to controlled drug delivery, and progress made on this subject are examined, with examples. |
| format | Article |
| id | doaj-art-335ecbf94ecf4facbe06ddabdd2e1b90 |
| institution | Kabale University |
| issn | 2651-4060 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Istanbul University Press |
| record_format | Article |
| series | Sabiad |
| spelling | doaj-art-335ecbf94ecf4facbe06ddabdd2e1b902025-08-20T03:53:07ZengIstanbul University PressSabiad2651-40602022-06-015212212910.26650/JARHS2022-1122852123456RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERYEsher Özçelikhttps://orcid.org/0000-0002-5611-1143Meryem Sedef Erdal0https://orcid.org/0000-0001-6220-2036Yıldız Özsoy Erginer1https://orcid.org/0000-0002-9110-3704İstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, TürkiyeConventional drug delivery systems can be inadequate in many areas today due to limiting factors such as the narrow therapeutic window, complex dosing interval in long-term treatments, and systemic toxicity. Accordingly, a search has been carried out for new controlled drug delivery systems, which aim to localize the pharmacological activity of the drug to the desired area at the desired rate, and exhibit increased activity with less complications for more drugs. Better patient compliance can be achieved with microfluidic-based drug delivery systems, which have been developed to meet these needs, and better release control can be achieved with advanced drug applications. These systems, created by the control and manipulation of nano/micro-sized liquids, have taken their place in the controlled release platform with a unique character on a single chip. This review provides general information about controlled drug release, then discusses biomedical devices, one of the new technologies developed through advancing research, and the microfluidic devices (micropumps and microneedles) that they utilize. Their types, structures, properties, preparation techniques, where they can be used and related applications, the advantages they can bring to controlled drug delivery, and progress made on this subject are examined, with examples.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/D49E40C0EBF54160B9E7D3B962A44EBFcontrolled drug deliverymicro/nanofluidic technologiesmicrofluidic devicesmicro pumpsmicroneedles |
| spellingShingle | Esher Özçelik Meryem Sedef Erdal Yıldız Özsoy Erginer RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERY Sabiad controlled drug delivery micro/nanofluidic technologies microfluidic devices micro pumps microneedles |
| title | RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERY |
| title_full | RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERY |
| title_fullStr | RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERY |
| title_full_unstemmed | RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERY |
| title_short | RECENT TECHNOLOGIES IN CONTROLLED RELEASE DRUG DELIVERY |
| title_sort | recent technologies in controlled release drug delivery |
| topic | controlled drug delivery micro/nanofluidic technologies microfluidic devices micro pumps microneedles |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/D49E40C0EBF54160B9E7D3B962A44EBF |
| work_keys_str_mv | AT esherozcelik recenttechnologiesincontrolledreleasedrugdelivery AT meryemsedeferdal recenttechnologiesincontrolledreleasedrugdelivery AT yıldızozsoyerginer recenttechnologiesincontrolledreleasedrugdelivery |