Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand

Background Long coronavirus disease (COVID) poses significant challenges for older adult patients, affecting their cardiopulmonary function and overall well-being. This study aimed to investigate the effects of slow deep breathing exercises on cardiopulmonary function, physical performance, biochemi...

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Main Authors: Tichanon Promsrisuk, Arunrat Srithawong, Ratchaniporn Kongsui, Napatr Sriraksa, Sitthisak Thongrong, Chiraphat Kloypan, Nattha Muangritdech, Kit Khunkitti, Thanakorn Thanawat, Petcharaporn Chachvarat
Format: Article
Language:English
Published: Korea Geriatrics Society 2025-06-01
Series:Annals of Geriatric Medicine and Research
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Online Access:http://www.e-agmr.org/upload/pdf/agmr-24-0175.pdf
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author Tichanon Promsrisuk
Arunrat Srithawong
Ratchaniporn Kongsui
Napatr Sriraksa
Sitthisak Thongrong
Chiraphat Kloypan
Nattha Muangritdech
Kit Khunkitti
Thanakorn Thanawat
Petcharaporn Chachvarat
author_facet Tichanon Promsrisuk
Arunrat Srithawong
Ratchaniporn Kongsui
Napatr Sriraksa
Sitthisak Thongrong
Chiraphat Kloypan
Nattha Muangritdech
Kit Khunkitti
Thanakorn Thanawat
Petcharaporn Chachvarat
author_sort Tichanon Promsrisuk
collection DOAJ
description Background Long coronavirus disease (COVID) poses significant challenges for older adult patients, affecting their cardiopulmonary function and overall well-being. This study aimed to investigate the effects of slow deep breathing exercises on cardiopulmonary function, physical performance, biochemical markers, oxidative stress, and stress levels in older adult patients with long COVID. Methods Sixty older adult patients with long COVID were randomly assigned to an exercise group of 30 patients and a control group of 30 patients. The exercise group engaged in slow deep breathing exercises for 30 minutes, five times a week over a period of 8 weeks, while the control group maintained their usual activities. Cardiovascular parameters, heart rate variability (HRV), respiratory muscle strength (RMS), pulmonary function tests (PFT), physical performance, biochemical and oxidative stress markers, and stress levels were assessed at baseline, 4 weeks, and 8 weeks. Data were analyzed using one-way repeated measures ANOVA. Results The exercise group showed significant reductions in cardiovascular parameters (systolic and diastolic blood pressure, pulse pressure, mean arterial pressure, and heart rate). Additionally, RMS, PFT, and physical performance showed significant increases. Improvements were also observed in HRV, biochemical markers (fasting blood sugar and lipid profile), oxidative stress markers (catalase, superoxide dismutase, and malondialdehyde), and stress levels. In contrast, no significant changes were found in the control group. Conclusion Slow deep breathing exercises, as a non-pharmacological intervention, significantly improve cardiopulmonary function, physical performance, and various health markers in older adult patients with long COVID. This approach provides a valuable and accessible therapeutic option for this population.
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series Annals of Geriatric Medicine and Research
spelling doaj-art-335cb63afd4143bd9b42b59e41d9d2cc2025-08-20T03:28:29ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982508-49092025-06-0129224025310.4235/agmr.24.01751190Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, ThailandTichanon Promsrisuk0Arunrat Srithawong1Ratchaniporn Kongsui2Napatr Sriraksa3Sitthisak Thongrong4Chiraphat Kloypan5Nattha Muangritdech6Kit Khunkitti7Thanakorn Thanawat8Petcharaporn Chachvarat9 Division of Physiology, School of Medical Sciences, University of Phayao, Phayao, Thailand Department of Physical Therapy, School of Allied Health Sciences, University of Phayao, Phayao, Thailand Division of Physiology, School of Medical Sciences, University of Phayao, Phayao, Thailand Division of Physiology, School of Medical Sciences, University of Phayao, Phayao, Thailand Division of Anatomy, School of Medical Sciences, University of Phayao, Phayao, Thailand Department of Pathology, School of Medicine, University of Phayao, Phayao, Thailand Khon Kaen University Phenome Centre, Khon Kaen University, Khon Kaen, Thailand Faculty of Science and Technology, Uttaradit Rajabhat University, Uttaradit, Thailand Faculty of Science and Technology, Uttaradit Rajabhat University, Uttaradit, Thailand Department of Internal Medicine, School of Medicine, University of Phayao, Phayao, ThailandBackground Long coronavirus disease (COVID) poses significant challenges for older adult patients, affecting their cardiopulmonary function and overall well-being. This study aimed to investigate the effects of slow deep breathing exercises on cardiopulmonary function, physical performance, biochemical markers, oxidative stress, and stress levels in older adult patients with long COVID. Methods Sixty older adult patients with long COVID were randomly assigned to an exercise group of 30 patients and a control group of 30 patients. The exercise group engaged in slow deep breathing exercises for 30 minutes, five times a week over a period of 8 weeks, while the control group maintained their usual activities. Cardiovascular parameters, heart rate variability (HRV), respiratory muscle strength (RMS), pulmonary function tests (PFT), physical performance, biochemical and oxidative stress markers, and stress levels were assessed at baseline, 4 weeks, and 8 weeks. Data were analyzed using one-way repeated measures ANOVA. Results The exercise group showed significant reductions in cardiovascular parameters (systolic and diastolic blood pressure, pulse pressure, mean arterial pressure, and heart rate). Additionally, RMS, PFT, and physical performance showed significant increases. Improvements were also observed in HRV, biochemical markers (fasting blood sugar and lipid profile), oxidative stress markers (catalase, superoxide dismutase, and malondialdehyde), and stress levels. In contrast, no significant changes were found in the control group. Conclusion Slow deep breathing exercises, as a non-pharmacological intervention, significantly improve cardiopulmonary function, physical performance, and various health markers in older adult patients with long COVID. This approach provides a valuable and accessible therapeutic option for this population.http://www.e-agmr.org/upload/pdf/agmr-24-0175.pdfpost-acute covid-19 syndromebreathing exercisesexercise tolerancelungaged
spellingShingle Tichanon Promsrisuk
Arunrat Srithawong
Ratchaniporn Kongsui
Napatr Sriraksa
Sitthisak Thongrong
Chiraphat Kloypan
Nattha Muangritdech
Kit Khunkitti
Thanakorn Thanawat
Petcharaporn Chachvarat
Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand
Annals of Geriatric Medicine and Research
post-acute covid-19 syndrome
breathing exercises
exercise tolerance
lung
aged
title Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand
title_full Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand
title_fullStr Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand
title_full_unstemmed Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand
title_short Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand
title_sort therapeutic effects of slow deep breathing on cardiopulmonary function physical performance biochemical parameters and stress in older adult patients with long covid in phayao thailand
topic post-acute covid-19 syndrome
breathing exercises
exercise tolerance
lung
aged
url http://www.e-agmr.org/upload/pdf/agmr-24-0175.pdf
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