In vitro and in vivo activity of sodium houttuyfonate and sodium new houttuyfonate against Candida auris infection by affecting adhesion, aggregation, and biofilm formation abilities

In vitro and in vivo activity of sodium houttuyfonate and sodium new houttuyfonate against Candida auris infection by affecting adhesion, aggregation, and biofilm formation abilities

ABSTRACT Candida auris is a rapidly spreading multidrug-resistant fungus that causes fatal infections under certain global conditions. Sodium houttuyfonate (SH) and sodium new houttuyfonate (SNH) are stable derivatives of houttuynin (decyl aldehyde) extracted from Houttuynia cordata, both possessing...

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Main Authors: Guangyuan Yang, Ruotong Yang, Xiaoxiao Zhu, Qianwen Xu, Xiaojia Niu, Chengui Miao, Wenfan Wei, Changzhong Wang, Tianming Wang, Daqiang Wu
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
Candida auris
sodium houttuyfonate
sodium new houttuyfonate
adhesion
aggregation
biofilm
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00222-25
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